A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy

Abstract Objective: To compare the effectiveness of zero-calorie soft drink and plain water as a solvent for sodium phosphate in terms of good palatability and better patient tolerance. Methods: The randomised controlled trial was conducted from May to December 2019 at the Dowites Operation The...

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Main Authors: Hina Khan, Amjad Siraj Memon, Mujeebur Rehman Abbasi, Khursheed Ahmed Samo, Jan Muhammad Agha, Lajpat Rathore, Summaya Saeed
Format: Article
Language:English
Published: Pakistan Medical Association 2022-02-01
Series:Journal of the Pakistan Medical Association
Online Access:https://www.ojs.jpma.org.pk/index.php/public_html/article/view/2344
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author Hina Khan
Amjad Siraj Memon
Mujeebur Rehman Abbasi
Khursheed Ahmed Samo
Jan Muhammad Agha
Lajpat Rathore
Summaya Saeed
author_facet Hina Khan
Amjad Siraj Memon
Mujeebur Rehman Abbasi
Khursheed Ahmed Samo
Jan Muhammad Agha
Lajpat Rathore
Summaya Saeed
author_sort Hina Khan
collection DOAJ
description Abstract Objective: To compare the effectiveness of zero-calorie soft drink and plain water as a solvent for sodium phosphate in terms of good palatability and better patient tolerance. Methods: The randomised controlled trial was conducted from May to December 2019 at the Dowites Operation Theatre Endoscopy Suite, Surgical Unit 3, Civil Hospital Karachi, and comprised patients aged >18 years of either gender undergoing colonoscopy for screening and non-emergency/non-urgent colorectal diseases. The patients were randomised into group A, which was assigned to take sodium phosphate in water, and group B, which was assigned to take sodium phosphate in zero-calorie soft drink. Bowel preparation was assessed by the consultant during endoscopy. Outcome variables, such as bowel cleanliness, palatability, tolerance of solution, adverse effects, and willingness to repeat the preparation, were evaluated in both groups. Data was analysed using SPSS 21. Results: Of the 162 patients, there were 81(50%) in each of the two groups. There were 124(76.5%) males and the overall mean age was 43±8.66 years. The palatability score was significant (p=0.01) for group B compared to group A. Due to better palatability and tolerance, 64(79%) patients in group B took the preparation in <6 hours. Conclusion: Use of zero-calorie soft drink was found to be a better option for colonoscopic preparation compared to plain water. Key Words: Zero calorie coke, Sodium phosphate.
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spelling doaj.art-51c39571723e49ccab2165ae6c67c36a2023-05-25T04:23:05ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822022-02-0172310.47391/JPMA.2344A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopyHina Khan0Amjad Siraj Memon1Mujeebur Rehman Abbasi2Khursheed Ahmed Samo3Jan Muhammad Agha4Lajpat Rathore5Summaya Saeed6Department of Surgery, Dow University of Health Sciences, Dr Ruth KM Pfau Civil hospital, Karachi, PakistanDepartment of Surgery, Dow University of Health Sciences, Dr Ruth KM Pfau Civil hospital, Karachi, PakistanDepartment of Surgery, Dow University of Health Sciences, Dr Ruth KM Pfau Civil hospital, Karachi, PakistanDepartment of Surgery, Dow University of Health Sciences, Dr Ruth KM Pfau Civil hospital, Karachi, PakistanDepartment of Surgery, Dr Ruth KM Pfau Civil hospital, Karachi, PakistanDepartment of Surgery, Dow University of Health Sciences, Karachi, PakistanDepartment of Surgery, Dow University of Health Sciences, Dr Ruth KM Pfau Civil hospital, Karachi, Pakistan Abstract Objective: To compare the effectiveness of zero-calorie soft drink and plain water as a solvent for sodium phosphate in terms of good palatability and better patient tolerance. Methods: The randomised controlled trial was conducted from May to December 2019 at the Dowites Operation Theatre Endoscopy Suite, Surgical Unit 3, Civil Hospital Karachi, and comprised patients aged >18 years of either gender undergoing colonoscopy for screening and non-emergency/non-urgent colorectal diseases. The patients were randomised into group A, which was assigned to take sodium phosphate in water, and group B, which was assigned to take sodium phosphate in zero-calorie soft drink. Bowel preparation was assessed by the consultant during endoscopy. Outcome variables, such as bowel cleanliness, palatability, tolerance of solution, adverse effects, and willingness to repeat the preparation, were evaluated in both groups. Data was analysed using SPSS 21. Results: Of the 162 patients, there were 81(50%) in each of the two groups. There were 124(76.5%) males and the overall mean age was 43±8.66 years. The palatability score was significant (p=0.01) for group B compared to group A. Due to better palatability and tolerance, 64(79%) patients in group B took the preparation in <6 hours. Conclusion: Use of zero-calorie soft drink was found to be a better option for colonoscopic preparation compared to plain water. Key Words: Zero calorie coke, Sodium phosphate. https://www.ojs.jpma.org.pk/index.php/public_html/article/view/2344
spellingShingle Hina Khan
Amjad Siraj Memon
Mujeebur Rehman Abbasi
Khursheed Ahmed Samo
Jan Muhammad Agha
Lajpat Rathore
Summaya Saeed
A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy
Journal of the Pakistan Medical Association
title A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy
title_full A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy
title_fullStr A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy
title_full_unstemmed A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy
title_short A prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy
title_sort prospective randomized trial to compare the effectiveness of zero calorie carbonated drink and water as a solvent in sodium phosphate for colonoscopy
url https://www.ojs.jpma.org.pk/index.php/public_html/article/view/2344
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