RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE
The establishment and application of animal models represent effective tools for research in rheumatoid arthritis (RA) pathogenesis. Animal models that replicate various mechanisms reflecting all aspects of RA, including early RA pathology, have provided important insights into studying etio...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2015-06-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/884 |
| _version_ | 1797198010580467712 |
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| author | I. A. Orlovskaya D. D. Tsyrendorzhiev S. N. Shchelkunov |
| author_facet | I. A. Orlovskaya D. D. Tsyrendorzhiev S. N. Shchelkunov |
| author_sort | I. A. Orlovskaya |
| collection | DOAJ |
| description | The establishment and application of animal models represent effective tools for research in rheumatoid arthritis (RA) pathogenesis. Animal models that replicate various mechanisms reflecting all aspects of RA, including early RA pathology, have provided important insights into studying etiology and pathogenetic mechanisms of RA in humans. This review article was compiled in order to give an introduction to the current state of RA models. Application of these experimental disorders for testing potential therapeutic approaches will help to make better predictions for drug efficiency in human RA |
| first_indexed | 2024-03-08T05:49:35Z |
| format | Article |
| id | doaj.art-51c52fa23a1647c8b54ebd72b5cfed8b |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:53:04Z |
| publishDate | 2015-06-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-51c52fa23a1647c8b54ebd72b5cfed8b2024-04-22T13:07:40ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2015-06-0117320321010.15789/1563-0625-2015-3-203-210776RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASEI. A. Orlovskaya0D. D. Tsyrendorzhiev1S. N. Shchelkunov2Research Institute of Basic and Clinical Immunology, NovosibirskResearch Institute of Basic and Clinical Immunology, NovosibirskState Research Center of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk regionThe establishment and application of animal models represent effective tools for research in rheumatoid arthritis (RA) pathogenesis. Animal models that replicate various mechanisms reflecting all aspects of RA, including early RA pathology, have provided important insights into studying etiology and pathogenetic mechanisms of RA in humans. This review article was compiled in order to give an introduction to the current state of RA models. Application of these experimental disorders for testing potential therapeutic approaches will help to make better predictions for drug efficiency in human RAhttps://www.mimmun.ru/mimmun/article/view/884rheumatoid arthritisexperimental modelspathogenesisetiologyanimalsimmunology |
| spellingShingle | I. A. Orlovskaya D. D. Tsyrendorzhiev S. N. Shchelkunov RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE Медицинская иммунология rheumatoid arthritis experimental models pathogenesis etiology animals immunology |
| title | RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE |
| title_full | RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE |
| title_fullStr | RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE |
| title_full_unstemmed | RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE |
| title_short | RHEUMATOID ARTHRITIS: LABORATORY MODELS OF THE DISEASE |
| title_sort | rheumatoid arthritis laboratory models of the disease |
| topic | rheumatoid arthritis experimental models pathogenesis etiology animals immunology |
| url | https://www.mimmun.ru/mimmun/article/view/884 |
| work_keys_str_mv | AT iaorlovskaya rheumatoidarthritislaboratorymodelsofthedisease AT ddtsyrendorzhiev rheumatoidarthritislaboratorymodelsofthedisease AT snshchelkunov rheumatoidarthritislaboratorymodelsofthedisease |