Towards Next-Generation Sequencing for HIV-1 Drug Resistance Testing in a Clinical Setting

Towards Next-Generation Sequencing for HIV-1 Drug Resistance Testing in a Clinical Setting

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The HIV genotypic resistance test (GRT) is a standard of care for the clinical management of HIV/AIDS patients. In recent decades, population or Sanger sequencing has been the foundation for drug resistance monitoring in clinical settings. However, the advent of high-throughput or next-generation se...

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Bibliographic Details
Main Authors: Calesta Hui Yi Teo, Nurul Hannah Binte Norhisham, Ogestelli Fabia Lee, Siyu Png, Chean Nee Chai, Gabriel Yan, Julian Wei-Tze Tang, Chun Kiat Lee
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
HIV-1
drug resistance
genotypic resistance testing
next-generation sequencing
high-throughput sequencing
Sanger
Online Access:https://www.mdpi.com/1999-4915/14/10/2208

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