Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano
Regeneration capable flatworms have emerged as powerful models for studying stem cell biology and patterning, however their study has been hindered by the lack of transgenesis methods. Here, the authors describe a transgenesis method for Macrostomum lignano, as well as a new annotated genome sequenc...
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-02214-8 |
| _version_ | 1818994869434056704 |
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| author | Jakub Wudarski Daniil Simanov Kirill Ustyantsev Katrien de Mulder Margriet Grelling Magda Grudniewska Frank Beltman Lisa Glazenburg Turan Demircan Julia Wunderer Weihong Qi Dita B. Vizoso Philipp M. Weissert Daniel Olivieri Stijn Mouton Victor Guryev Aziz Aboobaker Lukas Schärer Peter Ladurner Eugene Berezikov |
| author_facet | Jakub Wudarski Daniil Simanov Kirill Ustyantsev Katrien de Mulder Margriet Grelling Magda Grudniewska Frank Beltman Lisa Glazenburg Turan Demircan Julia Wunderer Weihong Qi Dita B. Vizoso Philipp M. Weissert Daniel Olivieri Stijn Mouton Victor Guryev Aziz Aboobaker Lukas Schärer Peter Ladurner Eugene Berezikov |
| author_sort | Jakub Wudarski |
| collection | DOAJ |
| description | Regeneration capable flatworms have emerged as powerful models for studying stem cell biology and patterning, however their study has been hindered by the lack of transgenesis methods. Here, the authors describe a transgenesis method for Macrostomum lignano, as well as a new annotated genome sequence. |
| first_indexed | 2024-12-20T21:04:48Z |
| format | Article |
| id | doaj.art-51c6474ac76046948c59094214f7739d |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T21:04:48Z |
| publishDate | 2017-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-51c6474ac76046948c59094214f7739d2022-12-21T19:26:38ZengNature PortfolioNature Communications2041-17232017-12-018111210.1038/s41467-017-02214-8Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignanoJakub Wudarski0Daniil Simanov1Kirill Ustyantsev2Katrien de Mulder3Margriet Grelling4Magda Grudniewska5Frank Beltman6Lisa Glazenburg7Turan Demircan8Julia Wunderer9Weihong Qi10Dita B. Vizoso11Philipp M. Weissert12Daniel Olivieri13Stijn Mouton14Victor Guryev15Aziz Aboobaker16Lukas Schärer17Peter Ladurner18Eugene Berezikov19European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1Institute of Cytology and Genetics, Prospekt Lavrentyeva 10Hubrecht Institute-KNAW and University Medical Centre Utrecht, Uppsalalaan 8European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1Hubrecht Institute-KNAW and University Medical Centre Utrecht, Uppsalalaan 8Institute of Zoology and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Technikerstr. 25Functional Genomics Center Zurich, Winterthurerstrasse 190Evolutionary Biology, Zoological Institute, University of Basel, Vesalgasse 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1Department of Zoology, University of Oxford, Tinbergen Building, South Parks RoadEvolutionary Biology, Zoological Institute, University of Basel, Vesalgasse 1Institute of Zoology and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Technikerstr. 25European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1Regeneration capable flatworms have emerged as powerful models for studying stem cell biology and patterning, however their study has been hindered by the lack of transgenesis methods. Here, the authors describe a transgenesis method for Macrostomum lignano, as well as a new annotated genome sequence.https://doi.org/10.1038/s41467-017-02214-8 |
| spellingShingle | Jakub Wudarski Daniil Simanov Kirill Ustyantsev Katrien de Mulder Margriet Grelling Magda Grudniewska Frank Beltman Lisa Glazenburg Turan Demircan Julia Wunderer Weihong Qi Dita B. Vizoso Philipp M. Weissert Daniel Olivieri Stijn Mouton Victor Guryev Aziz Aboobaker Lukas Schärer Peter Ladurner Eugene Berezikov Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano Nature Communications |
| title | Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano |
| title_full | Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano |
| title_fullStr | Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano |
| title_full_unstemmed | Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano |
| title_short | Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano |
| title_sort | efficient transgenesis and annotated genome sequence of the regenerative flatworm model macrostomum lignano |
| url | https://doi.org/10.1038/s41467-017-02214-8 |
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