Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)

The magnitude of occupational lead exposure and its impact on liver functions was assessed in battery manufacture workers around Kolhapur (Maharashtra). Blood lead, urine lead, erythrocyte zinc protoporphyrin, urine δ-amino laevulinic acid and porphobilinogen levels were measured together with stand...

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Main Author: Vinod.R.Bhagwat
Format: Article
Language:English
Published: Al Ameen Medical College 2008-06-01
Series:Al Ameen Journal of Medical Sciences
Subjects:
Online Access:http://ajms.alameenmedical.org/article_vol1/AJMS.Vol.01_No.01_2-9.corrected%20proof.pdf
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author Vinod.R.Bhagwat
author_facet Vinod.R.Bhagwat
author_sort Vinod.R.Bhagwat
collection DOAJ
description The magnitude of occupational lead exposure and its impact on liver functions was assessed in battery manufacture workers around Kolhapur (Maharashtra). Blood lead, urine lead, erythrocyte zinc protoporphyrin, urine δ-amino laevulinic acid and porphobilinogen levels were measured together with standard routine biochemical tests of liver functions in battery manufacture workers along with non-exposed controls subjects. Blood lead levels were considerably high in the workers (53.63 ± 16.98; range 25.8 – 78 μg/dl) compared to the controls (12.52 ± 4.08; range 2.8 - 22 μg/dl). The liver functions in these workers were normal, demonstrating preservation of hepatocellular and synthetic functions of liver. There was good correlation (r = 0.67) between blood lead and urinary δ-amino laevulinic acid levels in the worker group and no such correlation was observed in case of the control group (r = 0.02). The results indicates that early screening and regular monitoring of industrial workers by urinary δ-amino laevulinic acid levels is urgently needed to prevent long term adverse effects of lead exposure.
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spelling doaj.art-51c7889a529c409bbe8f4117ff7bc0612022-12-21T18:50:54ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11432008-06-01010129Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)Vinod.R.BhagwatThe magnitude of occupational lead exposure and its impact on liver functions was assessed in battery manufacture workers around Kolhapur (Maharashtra). Blood lead, urine lead, erythrocyte zinc protoporphyrin, urine δ-amino laevulinic acid and porphobilinogen levels were measured together with standard routine biochemical tests of liver functions in battery manufacture workers along with non-exposed controls subjects. Blood lead levels were considerably high in the workers (53.63 ± 16.98; range 25.8 – 78 μg/dl) compared to the controls (12.52 ± 4.08; range 2.8 - 22 μg/dl). The liver functions in these workers were normal, demonstrating preservation of hepatocellular and synthetic functions of liver. There was good correlation (r = 0.67) between blood lead and urinary δ-amino laevulinic acid levels in the worker group and no such correlation was observed in case of the control group (r = 0.02). The results indicates that early screening and regular monitoring of industrial workers by urinary δ-amino laevulinic acid levels is urgently needed to prevent long term adverse effects of lead exposure.http://ajms.alameenmedical.org/article_vol1/AJMS.Vol.01_No.01_2-9.corrected%20proof.pdfLeadOccupational exposureLiver functionsBattery recycling
spellingShingle Vinod.R.Bhagwat
Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)
Al Ameen Journal of Medical Sciences
Lead
Occupational exposure
Liver functions
Battery recycling
title Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)
title_full Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)
title_fullStr Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)
title_full_unstemmed Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)
title_short Occupational lead exposure and liver functions in battery manufacture workers around Kolhapur (Maharashtra)
title_sort occupational lead exposure and liver functions in battery manufacture workers around kolhapur maharashtra
topic Lead
Occupational exposure
Liver functions
Battery recycling
url http://ajms.alameenmedical.org/article_vol1/AJMS.Vol.01_No.01_2-9.corrected%20proof.pdf
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