Speech-Stimulating Substances in Autism Spectrum Disorders

Autism spectrum disorder (ASD) is characterized by the core domains of persistent deficits in social communication and restricted-repetitive patterns of behaviors, interests, or activities. A heterogeneous and complex set of neurodevelopmental conditions are grouped in the spectrum. Pro-inflammatory...

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Main Authors: María Andrea Castillo, Kendy Eduardo Urdaneta, Neomar Semprún-Hernández, Anna Lisa Brigida, Nicola Antonucci, Stephen Schultz, Dario Siniscalco
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Behavioral Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-328X/9/6/60
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author María Andrea Castillo
Kendy Eduardo Urdaneta
Neomar Semprún-Hernández
Anna Lisa Brigida
Nicola Antonucci
Stephen Schultz
Dario Siniscalco
author_facet María Andrea Castillo
Kendy Eduardo Urdaneta
Neomar Semprún-Hernández
Anna Lisa Brigida
Nicola Antonucci
Stephen Schultz
Dario Siniscalco
author_sort María Andrea Castillo
collection DOAJ
description Autism spectrum disorder (ASD) is characterized by the core domains of persistent deficits in social communication and restricted-repetitive patterns of behaviors, interests, or activities. A heterogeneous and complex set of neurodevelopmental conditions are grouped in the spectrum. Pro-inflammatory events and immune system dysfunctions are cellular and molecular events associated with ASD. Several conditions co-occur with ASD: seizures, gastro-intestinal problems, attention deficit, anxiety and depression, and sleep problems. However, language and speech issues are key components of ASD symptoms current therapies find difficult to face. Several speech-stimulating substances have been shown to be effective in increasing speech ability in ASD subjects. The need for large clinical trials to determine safety and efficacy is recommended.
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spelling doaj.art-51cf5febff23468094d8ccfdf852f0fb2022-12-22T01:12:57ZengMDPI AGBehavioral Sciences2076-328X2019-06-01966010.3390/bs9060060bs9060060Speech-Stimulating Substances in Autism Spectrum DisordersMaría Andrea Castillo0Kendy Eduardo Urdaneta1Neomar Semprún-Hernández2Anna Lisa Brigida3Nicola Antonucci4Stephen Schultz5Dario Siniscalco6Research Division, Autism Immunology Unit of Maracaibo, Maracaibo 4001, VenezuelaResearch Division, Autism Immunology Unit of Maracaibo, Maracaibo 4001, VenezuelaResearch Division, Autism Immunology Unit of Maracaibo, Maracaibo 4001, VenezuelaItalian Group for Studying Autism—GISA, 25018 Brescia, ItalyBiomedical Centre for Autism Research and Treatment, 70126 Bari, ItalyDepartment of Cellular and Integrative Physiology, School of Medicine, University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USADepartment of Experimental Medicine, University of Campania, 80138 Napoli, ItalyAutism spectrum disorder (ASD) is characterized by the core domains of persistent deficits in social communication and restricted-repetitive patterns of behaviors, interests, or activities. A heterogeneous and complex set of neurodevelopmental conditions are grouped in the spectrum. Pro-inflammatory events and immune system dysfunctions are cellular and molecular events associated with ASD. Several conditions co-occur with ASD: seizures, gastro-intestinal problems, attention deficit, anxiety and depression, and sleep problems. However, language and speech issues are key components of ASD symptoms current therapies find difficult to face. Several speech-stimulating substances have been shown to be effective in increasing speech ability in ASD subjects. The need for large clinical trials to determine safety and efficacy is recommended.https://www.mdpi.com/2076-328X/9/6/60autism spectrum disorderspeechlanguagenutrition
spellingShingle María Andrea Castillo
Kendy Eduardo Urdaneta
Neomar Semprún-Hernández
Anna Lisa Brigida
Nicola Antonucci
Stephen Schultz
Dario Siniscalco
Speech-Stimulating Substances in Autism Spectrum Disorders
Behavioral Sciences
autism spectrum disorder
speech
language
nutrition
title Speech-Stimulating Substances in Autism Spectrum Disorders
title_full Speech-Stimulating Substances in Autism Spectrum Disorders
title_fullStr Speech-Stimulating Substances in Autism Spectrum Disorders
title_full_unstemmed Speech-Stimulating Substances in Autism Spectrum Disorders
title_short Speech-Stimulating Substances in Autism Spectrum Disorders
title_sort speech stimulating substances in autism spectrum disorders
topic autism spectrum disorder
speech
language
nutrition
url https://www.mdpi.com/2076-328X/9/6/60
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AT neomarsemprunhernandez speechstimulatingsubstancesinautismspectrumdisorders
AT annalisabrigida speechstimulatingsubstancesinautismspectrumdisorders
AT nicolaantonucci speechstimulatingsubstancesinautismspectrumdisorders
AT stephenschultz speechstimulatingsubstancesinautismspectrumdisorders
AT dariosiniscalco speechstimulatingsubstancesinautismspectrumdisorders