Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell
The model of the semiconductor quantum dot with a multilayer shell and the quantum dot-human serum albumin bionanocomplex, which are contained in a living cell, was constructed. The regularities of changes in deformation of materials of the CdSe-core / ZnS/CdS/ZnS-shell quantum dot with changes in c...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Vasyl Stefanyk Precarpathian National University
2023-12-01
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| Series: | Фізика і хімія твердого тіла |
| Subjects: | |
| Online Access: | https://journals.pnu.edu.ua/index.php/pcss/article/view/7125 |
| _version_ | 1797234401156792320 |
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| author | O.V. Kuzyk O.O. Dan'kiv R.M. Peleshchak I.D. Stolyarchuk V.A. Kuhivchak |
| author_facet | O.V. Kuzyk O.O. Dan'kiv R.M. Peleshchak I.D. Stolyarchuk V.A. Kuhivchak |
| author_sort | O.V. Kuzyk |
| collection | DOAJ |
| description | The model of the semiconductor quantum dot with a multilayer shell and the quantum dot-human serum albumin bionanocomplex, which are contained in a living cell, was constructed. The regularities of changes in deformation of materials of the CdSe-core / ZnS/CdS/ZnS-shell quantum dot with changes in cell elasticity (comprehensive modulus) at different core radii, thicknesses of individual shell layers, and surface concentration of albumin molecules were investigated. It is shown that the presence of human serum albumin on the surface of the quantum dot significantly increases its sensitivity to pressure caused by the surrounding medium (living cell). The obtained results indicate the prospect of using the core-shell quantum dot-human serum albumin bionanocomplexes for the diagnosis of cancer diseases in the early stages. This is due to the fact that such diseases are accompanied by a sharp change in the elasticity of the cell (its elastic constants). |
| first_indexed | 2024-04-24T16:31:28Z |
| format | Article |
| id | doaj.art-51d10b735bfa468bb09d8d38397c43b1 |
| institution | Directory Open Access Journal |
| issn | 1729-4428 2309-8589 |
| language | English |
| last_indexed | 2024-04-24T16:31:28Z |
| publishDate | 2023-12-01 |
| publisher | Vasyl Stefanyk Precarpathian National University |
| record_format | Article |
| series | Фізика і хімія твердого тіла |
| spelling | doaj.art-51d10b735bfa468bb09d8d38397c43b12024-03-29T22:27:38ZengVasyl Stefanyk Precarpathian National UniversityФізика і хімія твердого тіла1729-44282309-85892023-12-0124467568110.15330/pcss.24.4.675-6816186Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cellO.V. KuzykO.O. Dan'kivR.M. PeleshchakI.D. StolyarchukV.A. KuhivchakThe model of the semiconductor quantum dot with a multilayer shell and the quantum dot-human serum albumin bionanocomplex, which are contained in a living cell, was constructed. The regularities of changes in deformation of materials of the CdSe-core / ZnS/CdS/ZnS-shell quantum dot with changes in cell elasticity (comprehensive modulus) at different core radii, thicknesses of individual shell layers, and surface concentration of albumin molecules were investigated. It is shown that the presence of human serum albumin on the surface of the quantum dot significantly increases its sensitivity to pressure caused by the surrounding medium (living cell). The obtained results indicate the prospect of using the core-shell quantum dot-human serum albumin bionanocomplexes for the diagnosis of cancer diseases in the early stages. This is due to the fact that such diseases are accompanied by a sharp change in the elasticity of the cell (its elastic constants).https://journals.pnu.edu.ua/index.php/pcss/article/view/7125core-shell quantum dothuman serum albumindeformationcomprehensive compression modulusliving cell |
| spellingShingle | O.V. Kuzyk O.O. Dan'kiv R.M. Peleshchak I.D. Stolyarchuk V.A. Kuhivchak Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell Фізика і хімія твердого тіла core-shell quantum dot human serum albumin deformation comprehensive compression modulus living cell |
| title | Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell |
| title_full | Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell |
| title_fullStr | Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell |
| title_full_unstemmed | Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell |
| title_short | Modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell |
| title_sort | modeling the deformation of the semiconductor quantum dot with a multilayer shell in a living cell |
| topic | core-shell quantum dot human serum albumin deformation comprehensive compression modulus living cell |
| url | https://journals.pnu.edu.ua/index.php/pcss/article/view/7125 |
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