Spontaneous intracranial hypotension: a case series and literature review

Spontaneous intracranial hypotension (SIH) is a condition of negative intracranial pressure resulting from cerebrospinal fluid (CSF) leakage from the dural sac and is a well-known cause of orthostatic headache. Diagnosis and management can be difficult, often requiring coordination between multiple...

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Main Authors: Michele Pistacchi, Andrea Pezzato, Roberta Rudà, Manuela Gioulis, Franco Contin, Federica Fragiacomo, Sandro Zambito Marsala
Format: Article
Language:English
Published: Termedia Publishing House 2023-04-01
Series:Folia Neuropathologica
Subjects:
Online Access:https://www.termedia.pl/Spontaneous-intracranial-hypotension-a-case-series-and-literature-review,20,50431,1,1.html
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author Michele Pistacchi
Andrea Pezzato
Roberta Rudà
Manuela Gioulis
Franco Contin
Federica Fragiacomo
Sandro Zambito Marsala
author_facet Michele Pistacchi
Andrea Pezzato
Roberta Rudà
Manuela Gioulis
Franco Contin
Federica Fragiacomo
Sandro Zambito Marsala
author_sort Michele Pistacchi
collection DOAJ
description Spontaneous intracranial hypotension (SIH) is a condition of negative intracranial pressure resulting from cerebrospinal fluid (CSF) leakage from the dural sac and is a well-known cause of orthostatic headache. Diagnosis and management can be difficult, often requiring coordination between multiple disciplines. Low CSF pressure and diffuse meningeal enhancement on brain MRI are the major instrumental features of the classic syndrome. Neuroimaging plays a key role in diagnosing SIH, particularly in atypical clinical presentations, by recognizing the specific findings of brain sagging on MRI and detecting the level of CSF leak on spinal imaging, thus guiding therapy accordingly. Since SIH could present with such a heterogeneous clinical picture, careful history taking and increased awareness of atypical presentations are of utmost importance. We review the existing SIH literature, illustrate management, clinical and neuroimaging findings of four consecutive patients with atypical SIH, who were recently referred to our hospital for evaluation to simplify and streamline the management of SIH.
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spelling doaj.art-51d19133235a4491b7c155b4517eb5de2023-12-01T11:36:45ZengTermedia Publishing HouseFolia Neuropathologica1641-46401509-572X2023-04-0161322523410.5114/fn.2023.12620950431Spontaneous intracranial hypotension: a case series and literature reviewMichele PistacchiAndrea PezzatoRoberta RudàManuela GioulisFranco ContinFederica FragiacomoSandro Zambito MarsalaSpontaneous intracranial hypotension (SIH) is a condition of negative intracranial pressure resulting from cerebrospinal fluid (CSF) leakage from the dural sac and is a well-known cause of orthostatic headache. Diagnosis and management can be difficult, often requiring coordination between multiple disciplines. Low CSF pressure and diffuse meningeal enhancement on brain MRI are the major instrumental features of the classic syndrome. Neuroimaging plays a key role in diagnosing SIH, particularly in atypical clinical presentations, by recognizing the specific findings of brain sagging on MRI and detecting the level of CSF leak on spinal imaging, thus guiding therapy accordingly. Since SIH could present with such a heterogeneous clinical picture, careful history taking and increased awareness of atypical presentations are of utmost importance. We review the existing SIH literature, illustrate management, clinical and neuroimaging findings of four consecutive patients with atypical SIH, who were recently referred to our hospital for evaluation to simplify and streamline the management of SIH.https://www.termedia.pl/Spontaneous-intracranial-hypotension-a-case-series-and-literature-review,20,50431,1,1.htmlorthostatic headache spontaneous intracranial hypotension low csf pressure
spellingShingle Michele Pistacchi
Andrea Pezzato
Roberta Rudà
Manuela Gioulis
Franco Contin
Federica Fragiacomo
Sandro Zambito Marsala
Spontaneous intracranial hypotension: a case series and literature review
Folia Neuropathologica
orthostatic headache
spontaneous intracranial hypotension
low csf pressure
title Spontaneous intracranial hypotension: a case series and literature review
title_full Spontaneous intracranial hypotension: a case series and literature review
title_fullStr Spontaneous intracranial hypotension: a case series and literature review
title_full_unstemmed Spontaneous intracranial hypotension: a case series and literature review
title_short Spontaneous intracranial hypotension: a case series and literature review
title_sort spontaneous intracranial hypotension a case series and literature review
topic orthostatic headache
spontaneous intracranial hypotension
low csf pressure
url https://www.termedia.pl/Spontaneous-intracranial-hypotension-a-case-series-and-literature-review,20,50431,1,1.html
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