Current status of vascularized composite tissue allotransplantation
Vascularized composite tissue allotransplantation (VCA) offers treatment options of complex functional deficiencies that cannot be repaired with conventional reconstructive methods. VCAs consist of blocks of functional units comprising different tissue types such as skin, bone, muscle, nerves, blood...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Oxford University Press
2014-04-01
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| Series: | Burns & Trauma |
| Subjects: | |
| Online Access: | http://www.burnstrauma.com/article.asp?issn=2321-3868;year=2014;volume=2;issue=2;spage=53;epage=60;aulast=Edtinger |
| _version_ | 1818260226902589440 |
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| author | Karoline Edtinger Xiaoyong Yang Hanae Uehara Stefan G Tullius |
| author_facet | Karoline Edtinger Xiaoyong Yang Hanae Uehara Stefan G Tullius |
| author_sort | Karoline Edtinger |
| collection | DOAJ |
| description | Vascularized composite tissue allotransplantation (VCA) offers treatment options of complex functional deficiencies that cannot be repaired with conventional reconstructive methods. VCAs consist of blocks of functional units comprising different tissue types such as skin, bone, muscle, nerves, blood vessels, tendons, ligaments and others, and are thus substantially different from the composition of organ transplants. The field of VCA has made fascinating progresses in the recent past. Among other VCAs, numerous successful hand, face and limb transplants have been performed in the world. At the same time, specific questions in regard to innate and adaptive immunity, consequences of ischemia/reperfusion injury, immunosuppression, preservation, and regenerative capacity remain. In spite of this, the field is poised to make significant advances in the near future. |
| first_indexed | 2024-12-12T18:27:58Z |
| format | Article |
| id | doaj.art-51d6afde7f3845a8a29a849de39fd5f4 |
| institution | Directory Open Access Journal |
| issn | 2321-3868 2321-3876 |
| language | English |
| last_indexed | 2024-12-12T18:27:58Z |
| publishDate | 2014-04-01 |
| publisher | Oxford University Press |
| record_format | Article |
| series | Burns & Trauma |
| spelling | doaj.art-51d6afde7f3845a8a29a849de39fd5f42022-12-22T00:16:00ZengOxford University PressBurns & Trauma2321-38682321-38762014-04-0122536010.4103/2321-3868.130184Current status of vascularized composite tissue allotransplantationKaroline EdtingerXiaoyong YangHanae UeharaStefan G TulliusVascularized composite tissue allotransplantation (VCA) offers treatment options of complex functional deficiencies that cannot be repaired with conventional reconstructive methods. VCAs consist of blocks of functional units comprising different tissue types such as skin, bone, muscle, nerves, blood vessels, tendons, ligaments and others, and are thus substantially different from the composition of organ transplants. The field of VCA has made fascinating progresses in the recent past. Among other VCAs, numerous successful hand, face and limb transplants have been performed in the world. At the same time, specific questions in regard to innate and adaptive immunity, consequences of ischemia/reperfusion injury, immunosuppression, preservation, and regenerative capacity remain. In spite of this, the field is poised to make significant advances in the near future.http://www.burnstrauma.com/article.asp?issn=2321-3868;year=2014;volume=2;issue=2;spage=53;epage=60;aulast=EdtingerFace transplantationhand transplantationimmunosuppressioncomposite tissue transplantation |
| spellingShingle | Karoline Edtinger Xiaoyong Yang Hanae Uehara Stefan G Tullius Current status of vascularized composite tissue allotransplantation Burns & Trauma Face transplantation hand transplantation immunosuppression composite tissue transplantation |
| title | Current status of vascularized composite tissue allotransplantation |
| title_full | Current status of vascularized composite tissue allotransplantation |
| title_fullStr | Current status of vascularized composite tissue allotransplantation |
| title_full_unstemmed | Current status of vascularized composite tissue allotransplantation |
| title_short | Current status of vascularized composite tissue allotransplantation |
| title_sort | current status of vascularized composite tissue allotransplantation |
| topic | Face transplantation hand transplantation immunosuppression composite tissue transplantation |
| url | http://www.burnstrauma.com/article.asp?issn=2321-3868;year=2014;volume=2;issue=2;spage=53;epage=60;aulast=Edtinger |
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