Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis

Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis

Summary: Proper lung function relies on the precise balance of specialized epithelial cells that coordinate to maintain homeostasis. Herein, we describe essential roles for the transcriptional regulators YAP/TAZ in maintaining lung epithelial homeostasis, reporting that conditional deletion of Yap a...

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Bibliographic Details
Main Authors: Julia Hicks-Berthet, Boting Ning, Anthony Federico, Andrew Tilston-Lunel, Adeline Matschulat, Xingbin Ai, Marc E. Lenburg, Jennifer Beane, Stefano Monti, Xaralabos Varelas
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
lung
goblet cell
Yap
Taz
Tead
Hippo
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721007233

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