DeepThy‐Net: A Multimodal Deep Learning Method for Predicting Cervical Lymph Node Metastasis in Papillary Thyroid Cancer

Papillary thyroid cancer (PTC) accounts for more than 80% of thyroid cancers, and ultrasound (US) imaging is the preferred method for the diagnosis of PTC. However, accurate prediction of different patterns of cervical lymph node metastasis (CLNM) in PTC continues to be a challenge. Herein, US image...

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מידע ביבליוגרפי
Main Authors: Jincao Yao, Zhikai Lei, Wenwen Yue, Bojian Feng, Wei Li, Di Ou, Na Feng, Yidan Lu, Jing Xu, Wencong Chen, Chen Yang, Lijing Wang, Liping Wang, Junping Liu, Peiying Wei, Huixiong Xu, Dong Xu
פורמט: Article
שפה:English
יצא לאור: Wiley 2022-10-01
סדרה:Advanced Intelligent Systems
נושאים:
גישה מקוונת:https://doi.org/10.1002/aisy.202200100
תיאור
סיכום:Papillary thyroid cancer (PTC) accounts for more than 80% of thyroid cancers, and ultrasound (US) imaging is the preferred method for the diagnosis of PTC. However, accurate prediction of different patterns of cervical lymph node metastasis (CLNM) in PTC continues to be a challenge. Herein, US images and clinical factors of PTC patients from three hospitals for more than 11 years are collected, and a multimodal deep learning model called DeepThy‐Net is then developed to predict different CLNM patterns. The proposed model not only uses the convolutional features extracted by deep learning but also integrates traditional clinical factors that are highly related to lymph node metastasis. Finally, the model is tested in two independent test sets, and the experimental results show that the area under curve (AUC) is between 0.870 and 0.905, indicating clinical applicability. The proposed method provides an important reference for the treatment and management of PTC. Moreover, for PTC cases involving an active surveillance strategy, the proposed method can serve as an important CLNM early warning tool.
ISSN:2640-4567