Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report
Abstract Background The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of t...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-11-01
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| Series: | BMC Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s12893-018-0426-z |
| _version_ | 1828499446834397184 |
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| author | Ma. Luisa Villalón Ma. De Los Ángeles Leal José R. Chávez Eduardo M. Santillán Ismael Lares-Asseff Verónica Loera Laura Valencia Blanca Camacho Brenda Alvarado Vilma Cervantes Leslie Patrón Horacio Almanza |
| author_facet | Ma. Luisa Villalón Ma. De Los Ángeles Leal José R. Chávez Eduardo M. Santillán Ismael Lares-Asseff Verónica Loera Laura Valencia Blanca Camacho Brenda Alvarado Vilma Cervantes Leslie Patrón Horacio Almanza |
| author_sort | Ma. Luisa Villalón |
| collection | DOAJ |
| description | Abstract Background The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. To our knowledge, this is the first described case of a patient with resection of dermoid cyst treated with human amniotic membrane implant and topical application of 0.02% mitomycin C. Case presentation We present a case of a 12-year-old male with a tumour in the superotemporal region of the right eye (RE). Symptoms included decreased visual acuity (VA), burning eye, foreign body sensation, and photophobia of the affected eye. A physical examination detected blepharospasm. Ophthalmic examination of his RE, fingers count from a 1–2 m distance, showed no improvement with pinhole. Visual acuity was 20/20 on the left eye (LE). The bio-microscopic examination confirmed the presence of a tumour mass (15 mm × 12 mm) on the surface of the RE, invading the superotemporal sector. The tumour had a lobulated appearance, a shiny and vascularized surface covered by conjunctiva, a pearlescent-pink colour, a medium consistency, was renitent and painless. An ultrasound scan revealed atrophy of the pigmented retinal epithelium with scleral indentation of the RE. A computed tomography (CT) scan revealed a recurrent lesion consistent with an epibulbar dermoid cyst. Surgical excision of the lesion was performed and a human amniotic membrane (HAM) graft and topical 0.02% mitomycin C (MMC) were applied. Histopathological analysis confirmed the diagnosis of recurrent dermoid cyst. Conclusion In this case report, we describe a case of recurrent epibulbar dermoid cyst treated with complete resection; topical MMC and HAM implant with good clinical outcome of the lesion and implant adhesion. Resection of a cyst of the ocular surface is not recommended when a large epibulbar dermoid tissue needs to be resected and no HAM graft is available. |
| first_indexed | 2024-12-11T13:24:45Z |
| format | Article |
| id | doaj.art-51d9a4de84cf4d0baaa8824ee58d4f04 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-12-11T13:24:45Z |
| publishDate | 2018-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-51d9a4de84cf4d0baaa8824ee58d4f042022-12-22T01:05:37ZengBMCBMC Surgery1471-24822018-11-011811810.1186/s12893-018-0426-zRecurrent epibulbar dermoid cyst treated with amniotic membrane implant a case reportMa. Luisa Villalón0Ma. De Los Ángeles Leal1José R. Chávez2Eduardo M. Santillán3Ismael Lares-Asseff4Verónica Loera5Laura Valencia6Blanca Camacho7Brenda Alvarado8Vilma Cervantes9Leslie Patrón10Horacio Almanza11The Californias’ Children Hospital Ophthalmology ServiceSchool of Health Sciences, Valle de Las Palmas, Autonomous University of Baja CaliforniaSchool of Health Sciences, Valle de Las Palmas, Autonomous University of Baja CaliforniaFray Junípero Serra Hospital, Security and Social Services Institute for State Workers, TijuanaInterdisciplinary Research Center for the Comprehensive Regional Development, Durango ModuleInterdisciplinary Research Center for the Comprehensive Regional Development, Durango ModuleDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja CaliforniaDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja CaliforniaDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja CaliforniaDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja CaliforniaDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja CaliforniaDepartment of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja CaliforniaAbstract Background The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. To our knowledge, this is the first described case of a patient with resection of dermoid cyst treated with human amniotic membrane implant and topical application of 0.02% mitomycin C. Case presentation We present a case of a 12-year-old male with a tumour in the superotemporal region of the right eye (RE). Symptoms included decreased visual acuity (VA), burning eye, foreign body sensation, and photophobia of the affected eye. A physical examination detected blepharospasm. Ophthalmic examination of his RE, fingers count from a 1–2 m distance, showed no improvement with pinhole. Visual acuity was 20/20 on the left eye (LE). The bio-microscopic examination confirmed the presence of a tumour mass (15 mm × 12 mm) on the surface of the RE, invading the superotemporal sector. The tumour had a lobulated appearance, a shiny and vascularized surface covered by conjunctiva, a pearlescent-pink colour, a medium consistency, was renitent and painless. An ultrasound scan revealed atrophy of the pigmented retinal epithelium with scleral indentation of the RE. A computed tomography (CT) scan revealed a recurrent lesion consistent with an epibulbar dermoid cyst. Surgical excision of the lesion was performed and a human amniotic membrane (HAM) graft and topical 0.02% mitomycin C (MMC) were applied. Histopathological analysis confirmed the diagnosis of recurrent dermoid cyst. Conclusion In this case report, we describe a case of recurrent epibulbar dermoid cyst treated with complete resection; topical MMC and HAM implant with good clinical outcome of the lesion and implant adhesion. Resection of a cyst of the ocular surface is not recommended when a large epibulbar dermoid tissue needs to be resected and no HAM graft is available.http://link.springer.com/article/10.1186/s12893-018-0426-zDermoid cystAmniotic membraneMitomycin c |
| spellingShingle | Ma. Luisa Villalón Ma. De Los Ángeles Leal José R. Chávez Eduardo M. Santillán Ismael Lares-Asseff Verónica Loera Laura Valencia Blanca Camacho Brenda Alvarado Vilma Cervantes Leslie Patrón Horacio Almanza Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report BMC Surgery Dermoid cyst Amniotic membrane Mitomycin c |
| title | Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report |
| title_full | Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report |
| title_fullStr | Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report |
| title_full_unstemmed | Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report |
| title_short | Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report |
| title_sort | recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report |
| topic | Dermoid cyst Amniotic membrane Mitomycin c |
| url | http://link.springer.com/article/10.1186/s12893-018-0426-z |
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