Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells

Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells

Abstract Background In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of the dorsal aorta and subsequently migrate to secondary niches where they expand and differentiate into committed lineages. Glia maturation factor γ (gmfg) is a key re...

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Bibliographic Details
Main Authors: Honghu Li, Qian Luo, Shuyang Cai, Ruxiu Tie, Ye Meng, Wei Shan, Yulin Xu, Xiangjun Zeng, Pengxu Qian, He Huang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Glia maturation factor-γ
HSPC
Blood flow
Yap
Notch
Zebrafish
Online Access:https://doi.org/10.1186/s13287-023-03328-1

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