Integrating Network Analysis and Metabolomics to Reveal Mechanism of Huaganjian Decoction in Treatment of Cholestatic Hepatic Injury

Integrating Network Analysis and Metabolomics to Reveal Mechanism of Huaganjian Decoction in Treatment of Cholestatic Hepatic Injury

Huaganjian decoction (HGJD) was first recorded in the classic “Jing Yue Quan Shu” during the Ming dynasty, and it has been extensively applied in clinical practice to treat liver diseases for over 300 years in China. However, its bioactive constituents and relevant pharmacological mechanism are stil...

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Bibliographic Details
Main Authors: Qin Dong, Jiao Chen, Yan-Ping Jiang, Zong-Ping Zhu, Yong-Feng Zheng, Jin-Ming Zhang, Zhen Zhang, Wen-Qing Chen, Shi-Yi Sun, Lan Pang, Xin Yan, Wan Liao, Chao-Mei Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
huaganjian decoction
cholestatic hepatic injury
metabolomics
serum pharmacochemistry
network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.773957/full

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