Impact of intravesical Bacillus Calmette-Guérin and chemotherapy on the bladder microbiome in patients with non-muscle invasive bladder cancer

Impact of intravesical Bacillus Calmette-Guérin and chemotherapy on the bladder microbiome in patients with non-muscle invasive bladder cancer

IntroductionIntravesical therapy (IVT), including Bacillus Calmette-Guérin (BCG), is the standard of care for high grade (HG) non-muscle invasive bladder cancer (NMIBC). Despite the use of IVT, many patients recur after treatment. The bladder microbiome and its role in disease processes has recently...

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Bibliographic Details
Main Authors: Christopher James, Kayeromi Gomez, Shalin Desai, Hiten D. Patel, Goran Rac, Chirag P. Doshi, Ryan Dornbier, Petar Bajic, Thomas Halverson, Gopal N. Gupta, Marcus L. Quek, Alex Gorbonos, Robert Flanigan, Alan J. Wolfe
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Bacillus Calmette-Guérin (BCG)
intravesical therapy
microbiome
bladder cancer
intravesical gemcitabine
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1125809/full

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