Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue
IntroductionArthrodesis, performed as a salvage surgical procedure to treat intractable joint conditions in dogs and cats, is associated with a high incidence of complications intra and postoperative, proving the need for improved and new techniques in arthrodesis surgery. Adding a new resorbable bo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2023.1250147/full |
| _version_ | 1797679226460045312 |
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| author | Tobias Per Otto Lundin Michael Pujari-Palmer Gustaf Svensson Odd Viking Höglund |
| author_facet | Tobias Per Otto Lundin Michael Pujari-Palmer Gustaf Svensson Odd Viking Höglund |
| author_sort | Tobias Per Otto Lundin |
| collection | DOAJ |
| description | IntroductionArthrodesis, performed as a salvage surgical procedure to treat intractable joint conditions in dogs and cats, is associated with a high incidence of complications intra and postoperative, proving the need for improved and new techniques in arthrodesis surgery. Adding a new resorbable bone glue to the arthrodesis could potentially add fixation strength and lower complications. The objectives of this experimental ex vivo biomechanical study were therefore to develop a biomechanical test model of partial tarsal arthrodesis and to determine whether the new resorbable bone glue (phosphoserine modified cement) produced measurable fixation strength in canine calcaneoquartal arthrodesis, without orthopedic implants.MethodsFour biomechanical test models with a total of 35 canine tarsal joints were used. Soft tissues were dissected to 4 different test models with variable contributions from soft tissues. The calcaneoquartal joint was prepared as in vivo arthrodesis and the glue was applied to joint surfaces as a liquid/putty (0.4 cc). After curing for 24 h, a shear force was applied to the joint (1 mm per minute) and the failure strength was recorded.ResultsCalcaneoquartal joints, where all soft tissues had been completely resected and fixated with glue (1–1.5 cm2 joint surface), withstood 2–5 mm of displacement and an average of 100 ± 58 N/cm2 of shear force (Model 1). Similar adhesive fixation strengths were obtained in Model 2 and 3 with increasing contributions from soft tissues (80 ± 44 and 63 ± 23 N/cm2, p = 0.39, ANOVA).ConclusionThe developed biomechanical model was sensitive enough to measure differences in fixation strengths between different glue formulations. The average fixation strength (60–100 N/cm2) should be strong enough to support short-term load bearing in medium sized canines (20 kg). The developed cadaver biomechanical test model is of potential use for other arthrodesis studies. The new resorbable glue can potentially contribute to stability at arthrodesis surgery, acting as a complement to today’s standard fixation, metal implants. |
| first_indexed | 2024-03-11T23:11:26Z |
| format | Article |
| id | doaj.art-51de8d13ce4c4fafb8dac7cebd314036 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-03-11T23:11:26Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-51de8d13ce4c4fafb8dac7cebd3140362023-09-21T07:54:47ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692023-09-011010.3389/fvets.2023.12501471250147Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glueTobias Per Otto Lundin0Michael Pujari-Palmer1Gustaf Svensson2Odd Viking Höglund3Department of Surgery, Blå Stjärnans Djursjukhus, Gothenburg, SwedenDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SwedenDepartment of Surgery, Blå Stjärnans Djursjukhus, Gothenburg, SwedenDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, SwedenIntroductionArthrodesis, performed as a salvage surgical procedure to treat intractable joint conditions in dogs and cats, is associated with a high incidence of complications intra and postoperative, proving the need for improved and new techniques in arthrodesis surgery. Adding a new resorbable bone glue to the arthrodesis could potentially add fixation strength and lower complications. The objectives of this experimental ex vivo biomechanical study were therefore to develop a biomechanical test model of partial tarsal arthrodesis and to determine whether the new resorbable bone glue (phosphoserine modified cement) produced measurable fixation strength in canine calcaneoquartal arthrodesis, without orthopedic implants.MethodsFour biomechanical test models with a total of 35 canine tarsal joints were used. Soft tissues were dissected to 4 different test models with variable contributions from soft tissues. The calcaneoquartal joint was prepared as in vivo arthrodesis and the glue was applied to joint surfaces as a liquid/putty (0.4 cc). After curing for 24 h, a shear force was applied to the joint (1 mm per minute) and the failure strength was recorded.ResultsCalcaneoquartal joints, where all soft tissues had been completely resected and fixated with glue (1–1.5 cm2 joint surface), withstood 2–5 mm of displacement and an average of 100 ± 58 N/cm2 of shear force (Model 1). Similar adhesive fixation strengths were obtained in Model 2 and 3 with increasing contributions from soft tissues (80 ± 44 and 63 ± 23 N/cm2, p = 0.39, ANOVA).ConclusionThe developed biomechanical model was sensitive enough to measure differences in fixation strengths between different glue formulations. The average fixation strength (60–100 N/cm2) should be strong enough to support short-term load bearing in medium sized canines (20 kg). The developed cadaver biomechanical test model is of potential use for other arthrodesis studies. The new resorbable glue can potentially contribute to stability at arthrodesis surgery, acting as a complement to today’s standard fixation, metal implants.https://www.frontiersin.org/articles/10.3389/fvets.2023.1250147/fullarthrodesisfixationstabilitybiomechanical modelglueadhesive |
| spellingShingle | Tobias Per Otto Lundin Michael Pujari-Palmer Gustaf Svensson Odd Viking Höglund Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue Frontiers in Veterinary Science arthrodesis fixation stability biomechanical model glue adhesive |
| title | Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue |
| title_full | Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue |
| title_fullStr | Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue |
| title_full_unstemmed | Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue |
| title_short | Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue |
| title_sort | canine ex vivo tarsal arthrodesis fixation by using a new bone tissue glue |
| topic | arthrodesis fixation stability biomechanical model glue adhesive |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2023.1250147/full |
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