Leukotriene B4 receptor knockdown affects PI3K/AKT/mTOR signaling and apoptotic responses in colorectal cancer

Leukotriene B4 receptor knockdown affects PI3K/AKT/mTOR signaling and apoptotic responses in colorectal cancer

Colorectal cancer (CRC) presents a landscape of intricate molecular dynamics. In this study, we focused on the role of the leukotriene B4 receptor (LTB4R) in CRC, exploring its significance in the disease's progression and potential therapeutic approaches. Using bioinformatics analysis of the...

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Bibliographic Details
Main Authors:	Cui Tang, Aili Wang, YanLin Zhao, WenYing Mou, Jun Jiang, Jie Kuang, Bin Sun, Erjiang Tang
Format:	Article
Language:	English
Published:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2024-01-01
Series:	Biomolecules & Biomedicine
Subjects:	Leukotriene B4 receptor (LTB4R) colorectal cancer (CRC) phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling pathway apoptosis
Online Access:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/10119

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