Comprehensive Interactome Analysis for the Sole Adenylyl Cyclase Cyr1 of Candida albicans

Comprehensive Interactome Analysis for the Sole Adenylyl Cyclase Cyr1 of Candida albicans

ABSTRACT Cyr1, the sole adenylyl cyclase of the fungal pathogen Candida albicans, is a central component of the cAMP/protein kinase A signaling pathway that controls the yeast-to-hypha transition. Cyr1 is a multivalent sensor and integrator of various external and internal signals. To better underst...

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Bibliographic Details
Main Authors: Guisheng Zeng, Suat Peng Neo, Li Mei Pang, Jiaxin Gao, Shu Chen Chong, Jayantha Gunaratne, Yue Wang
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
Candida albicans
Cyr1
SILAC
adenylyl cyclase
mass spectrometry
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03934-22

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