Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging

Polarization imaging can quantitatively probe the microscopic structure of biological tissues which can be complex and consist of layered structures. In this paper, we established a fast-backscattering Mueller matrix imaging system to characterize the dynamic variation in the microstructure of singl...

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Bibliographic Details
Main Authors: Tongjun Bu, Conghui Shao, Yuanhuan Zhu, Tongyu Huang, Qianhao Zhao, Yanan Sun, Yi Wang, Hui Ma
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Photonics
Subjects:
Online Access:https://www.mdpi.com/2304-6732/9/3/153
Description
Summary:Polarization imaging can quantitatively probe the microscopic structure of biological tissues which can be complex and consist of layered structures. In this paper, we established a fast-backscattering Mueller matrix imaging system to characterize the dynamic variation in the microstructure of single-layer and double-layer tissues as glycerin solution penetrated into the samples. The characteristic response of Mueller matrix elements, as well as polarization parameters with clearer physics meanings, show that polarization imaging can capture the dynamic variation in the layered microstructure. The experimental results are confirmed by Monte Carlo simulations. Further examination on the accuracy of Mueller matrix measurements also shows that much faster speed has to be considered when backscattering Mueller matrix imaging is applied to living samples.
ISSN:2304-6732