Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging

Polarization imaging can quantitatively probe the microscopic structure of biological tissues which can be complex and consist of layered structures. In this paper, we established a fast-backscattering Mueller matrix imaging system to characterize the dynamic variation in the microstructure of singl...

Full description

Bibliographic Details
Main Authors: Tongjun Bu, Conghui Shao, Yuanhuan Zhu, Tongyu Huang, Qianhao Zhao, Yanan Sun, Yi Wang, Hui Ma
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Photonics
Subjects:
Online Access:https://www.mdpi.com/2304-6732/9/3/153
_version_ 1797443490379988992
author Tongjun Bu
Conghui Shao
Yuanhuan Zhu
Tongyu Huang
Qianhao Zhao
Yanan Sun
Yi Wang
Hui Ma
author_facet Tongjun Bu
Conghui Shao
Yuanhuan Zhu
Tongyu Huang
Qianhao Zhao
Yanan Sun
Yi Wang
Hui Ma
author_sort Tongjun Bu
collection DOAJ
description Polarization imaging can quantitatively probe the microscopic structure of biological tissues which can be complex and consist of layered structures. In this paper, we established a fast-backscattering Mueller matrix imaging system to characterize the dynamic variation in the microstructure of single-layer and double-layer tissues as glycerin solution penetrated into the samples. The characteristic response of Mueller matrix elements, as well as polarization parameters with clearer physics meanings, show that polarization imaging can capture the dynamic variation in the layered microstructure. The experimental results are confirmed by Monte Carlo simulations. Further examination on the accuracy of Mueller matrix measurements also shows that much faster speed has to be considered when backscattering Mueller matrix imaging is applied to living samples.
first_indexed 2024-03-09T12:56:50Z
format Article
id doaj.art-51e272f962114356a2cad595302f177d
institution Directory Open Access Journal
issn 2304-6732
language English
last_indexed 2024-03-09T12:56:50Z
publishDate 2022-03-01
publisher MDPI AG
record_format Article
series Photonics
spelling doaj.art-51e272f962114356a2cad595302f177d2023-11-30T21:58:57ZengMDPI AGPhotonics2304-67322022-03-019315310.3390/photonics9030153Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization ImagingTongjun Bu0Conghui Shao1Yuanhuan Zhu2Tongyu Huang3Qianhao Zhao4Yanan Sun5Yi Wang6Hui Ma7Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaDepartment of Physics, Tsinghua University, Beijing 100084, ChinaTsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen 518055, ChinaDepartment of Biomedical Engineering, Tsinghua University, Beijing 100084, ChinaShenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaExperimental Research Center, China Academy of Chinese Medicine Science, Beijing 100091, ChinaExperimental Research Center, China Academy of Chinese Medicine Science, Beijing 100091, ChinaShenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaPolarization imaging can quantitatively probe the microscopic structure of biological tissues which can be complex and consist of layered structures. In this paper, we established a fast-backscattering Mueller matrix imaging system to characterize the dynamic variation in the microstructure of single-layer and double-layer tissues as glycerin solution penetrated into the samples. The characteristic response of Mueller matrix elements, as well as polarization parameters with clearer physics meanings, show that polarization imaging can capture the dynamic variation in the layered microstructure. The experimental results are confirmed by Monte Carlo simulations. Further examination on the accuracy of Mueller matrix measurements also shows that much faster speed has to be considered when backscattering Mueller matrix imaging is applied to living samples.https://www.mdpi.com/2304-6732/9/3/153dynamicspolarizationbackscatteringMueller matrix
spellingShingle Tongjun Bu
Conghui Shao
Yuanhuan Zhu
Tongyu Huang
Qianhao Zhao
Yanan Sun
Yi Wang
Hui Ma
Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging
Photonics
dynamics
polarization
backscattering
Mueller matrix
title Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging
title_full Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging
title_fullStr Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging
title_full_unstemmed Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging
title_short Probing Dynamic Variation of Layered Microstructure Using Backscattering Polarization Imaging
title_sort probing dynamic variation of layered microstructure using backscattering polarization imaging
topic dynamics
polarization
backscattering
Mueller matrix
url https://www.mdpi.com/2304-6732/9/3/153
work_keys_str_mv AT tongjunbu probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging
AT conghuishao probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging
AT yuanhuanzhu probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging
AT tongyuhuang probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging
AT qianhaozhao probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging
AT yanansun probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging
AT yiwang probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging
AT huima probingdynamicvariationoflayeredmicrostructureusingbackscatteringpolarizationimaging