Collective feature selection to identify crucial epistatic variants
Abstract Background Machine learning methods have gained popularity and practicality in identifying linear and non-linear effects of variants associated with complex disease/traits. Detection of epistatic interactions still remains a challenge due to the large number of features and relatively small...
Main Authors: | Shefali S. Verma, Anastasia Lucas, Xinyuan Zhang, Yogasudha Veturi, Scott Dudek, Binglan Li, Ruowang Li, Ryan Urbanowicz, Jason H. Moore, Dokyoon Kim, Marylyn D. Ritchie |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | BioData Mining |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13040-018-0168-6 |
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