NAMPT-mediated salvage synthesis of NAD+ controls morphofunctional changes of macrophages.

NAMPT-mediated salvage synthesis of NAD+ controls morphofunctional changes of macrophages.

Functional morphodynamic behavior of differentiated macrophages is strongly controlled by actin cytoskeleton rearrangements, a process in which also metabolic cofactors ATP and NAD(H) (i.e. NAD+ and NADH) and NADP(H) (i.e. NADP+ and NADPH) play an essential role. Whereas the link to intracellular AT...

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Bibliographic Details
Main Authors: Gerda Venter, Frank T J J Oerlemans, Marieke Willemse, Mietske Wijers, Jack A M Fransen, Bé Wieringa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4019579?pdf=render

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http://europepmc.org/articles/PMC4019579?pdf=render

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