Gingival crevicular fluid in the diagnosis of periodontal and systemic diseases
Gingival crevicular fluid (GCF) can be found in the physiologic space (gingival sulcus), as well as in the pathological space (gingival pocket or periodontal pocket) between the gums and teeth. In the first case it is a transudate, in the second an exudate. The constituents of GCF originate from ser...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2009-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2009/0370-81790906298C.pdf |
| _version_ | 1828861896364654592 |
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| author | Čakić Saša |
| author_facet | Čakić Saša |
| author_sort | Čakić Saša |
| collection | DOAJ |
| description | Gingival crevicular fluid (GCF) can be found in the physiologic space (gingival sulcus), as well as in the pathological space (gingival pocket or periodontal pocket) between the gums and teeth. In the first case it is a transudate, in the second an exudate. The constituents of GCF originate from serum, gingival tissues, and from both bacterial and host response cells present in the aforementioned spaces and the surrounding tissues. The collection and analysis of GCF are the noninvasive methods for the evaluation of host response in periodontal disease. These analyses mainly focus on inflammatory markers, such as prostaglandin E2, neutrophil elastase and β-glucuronidase, and on the marker of cellular necrosis - aspartat aminotransferase. Further, the analysis of inflammatory markers in the GCF may assist in defining how certain systemic diseases (e.g., diabetes mellitus) can modify periodontal disease, and how peridontal disease can influence certain systemic disorders (atherosclerosis, preterm delivery, diabetes mellitus and some chronic respiratory diseases). Major factors which influence the results obtained from the analyses of GCF are not only the methods of these analyses, but the method of GCF collection as well. As saliva collection is less technique-sensitive than GCF collection, some constituents of saliva which originate from the GCF can be analyzed as more amenable to chairside utilization. |
| first_indexed | 2024-12-13T03:11:38Z |
| format | Article |
| id | doaj.art-51e4f92f89cd4944aa702491480736b4 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 |
| language | English |
| last_indexed | 2024-12-13T03:11:38Z |
| publishDate | 2009-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-51e4f92f89cd4944aa702491480736b42022-12-22T00:01:34ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792009-01-011375-629830310.2298/SARH0906298CGingival crevicular fluid in the diagnosis of periodontal and systemic diseasesČakić SašaGingival crevicular fluid (GCF) can be found in the physiologic space (gingival sulcus), as well as in the pathological space (gingival pocket or periodontal pocket) between the gums and teeth. In the first case it is a transudate, in the second an exudate. The constituents of GCF originate from serum, gingival tissues, and from both bacterial and host response cells present in the aforementioned spaces and the surrounding tissues. The collection and analysis of GCF are the noninvasive methods for the evaluation of host response in periodontal disease. These analyses mainly focus on inflammatory markers, such as prostaglandin E2, neutrophil elastase and β-glucuronidase, and on the marker of cellular necrosis - aspartat aminotransferase. Further, the analysis of inflammatory markers in the GCF may assist in defining how certain systemic diseases (e.g., diabetes mellitus) can modify periodontal disease, and how peridontal disease can influence certain systemic disorders (atherosclerosis, preterm delivery, diabetes mellitus and some chronic respiratory diseases). Major factors which influence the results obtained from the analyses of GCF are not only the methods of these analyses, but the method of GCF collection as well. As saliva collection is less technique-sensitive than GCF collection, some constituents of saliva which originate from the GCF can be analyzed as more amenable to chairside utilization.http://www.doiserbia.nb.rs/img/doi/0370-8179/2009/0370-81790906298C.pdfgingival crevicular fluiddiagnosisperiodontal disease |
| spellingShingle | Čakić Saša Gingival crevicular fluid in the diagnosis of periodontal and systemic diseases Srpski Arhiv za Celokupno Lekarstvo gingival crevicular fluid diagnosis periodontal disease |
| title | Gingival crevicular fluid in the diagnosis of periodontal and systemic diseases |
| title_full | Gingival crevicular fluid in the diagnosis of periodontal and systemic diseases |
| title_fullStr | Gingival crevicular fluid in the diagnosis of periodontal and systemic diseases |
| title_full_unstemmed | Gingival crevicular fluid in the diagnosis of periodontal and systemic diseases |
| title_short | Gingival crevicular fluid in the diagnosis of periodontal and systemic diseases |
| title_sort | gingival crevicular fluid in the diagnosis of periodontal and systemic diseases |
| topic | gingival crevicular fluid diagnosis periodontal disease |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2009/0370-81790906298C.pdf |
| work_keys_str_mv | AT cakicsasa gingivalcrevicularfluidinthediagnosisofperiodontalandsystemicdiseases |