A Protein in the Yeast <i>Saccharomyces cerevisiae</i> Presents DNA Binding Homology to the p53 Checkpoint Protein and Tumor Suppressor

A Protein in the Yeast <i>Saccharomyces cerevisiae</i> Presents DNA Binding Homology to the p53 Checkpoint Protein and Tumor Suppressor

<i>Saccharomyces cerevisiae</i> does not contain a p53 homolog. Utilizing this yeast as an in vivo test tube model, our aim was to investigate if a yeast protein would show p53 DNA binding homology. Electrophoretic mobility shift analyses revealed the formation of specific DNA-protein co...

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Bibliographic Details
Main Authors: Kanwal Farooqi, Marjan Ghazvini, Leah D. Pride, Louis Mazzella, David White, Ajay Pramanik, Jill Bargonetti, Carol Wood Moore
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
p53 response elements
yeast
scs
mdm2
transactivation
p53 dna binding sites
p53 binding site factor
<i>saccharomyes cerevisiae</i>
Online Access:https://www.mdpi.com/2218-273X/10/3/417

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