S<sub>N</sub>Ar Reactions on 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde

S<sub>N</sub>Ar Reactions on 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde

We report the experimental results of unexpected aromatic nucleophilic substitution reaction products on 2-amino-4,6-dichloropyrimidine-5-carbaldehyde. The isolated compounds are products of amination, solvolysis, and condensation processes under mild and environmentally friendly conditions, due to...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Jorge Trilleras, Alfredo Pérez-Gamboa, Jairo Quiroga
التنسيق:	مقال
اللغة:	English
منشور في:	MDPI AG 2022-08-01
سلاسل:	Molbank
الموضوعات:	amination dichloropyrimidines aromatic substitution
الوصول للمادة أونلاين:	https://www.mdpi.com/1422-8599/2022/3/M1426

مواد مشابهة

Mono- and Diamination of 4,6-Dichloropyrimidine, 2,6-Dichloropyrazine and 1,3-Dichloroisoquinoline with Adamantane-Containing Amines
حسب: Alisa D. Kharlamova, وآخرون
منشور في: (2021-03-01)

UM MÉTODO EFICIENTE PARA A OBTENÇÃO DE DERIVADOS DE 1-ALQUILAMINO-2,4-DINITROBENZENO E A REDUÇÃO REGIOSSELETIVA PARA A OBTENÇÃO DE DERIVADOS DE 1-ALQUILAMINO-2-AMINO-4-NITROBENZENO
حسب: Cíntia de A. Custódio, وآخرون
منشور في: (2016-01-01)

A second monoclinic polymorph of 2-amino-4,6-dichloropyrimidine
حسب: Shyamaprosad Goswami, وآخرون
منشور في: (2008-09-01)

Leaving group ability in nucleophilic aromatic amination by sodium hydride-lithium iodide composite
حسب: Pang, Jia Hao, وآخرون
منشور في: (2022)

Nucleophilic Aromatic Substitution of Polyfluoroarene to Access Highly Functionalized 10-Phenylphenothiazine Derivatives
حسب: Kotaro Kikushima, وآخرون
منشور في: (2021-03-01)

Photoredox Catalyzed Dealkylative Aromatic Halogen Substitution with Tertiary Amines
حسب: Dmitry L. Lipilin, وآخرون
منشور في: (2021-06-01)

Effect of time and temperature on the simultaneous formation of heterocyclic amines and polycyclic aromatic hydrocarbons using amino acid and sugar model systems
حسب: Ishak, Ainaatul Asmaa'
منشور في: (2021)

Reações de 1,2-dicloro-4,5-dinitrobenzeno com aminas: monossubstituição de nitro e dissubstituição de cloro e nitro Reactions of 1,2-dichloro-4,5-dinitrobenzene with amines: monosubstitution of chlorine and disubstitution of chlorine and nitro
حسب: Fabrício Gava Menezes, وآخرون
منشور في: (2007-04-01)

Post Synthetic Modification of Planar Antiaromatic Hexaphyrin (1.0.1.0.1.0) by Regio-Selective, Sequential S<sub>N</sub>Ar
حسب: Ranjan Dutta, وآخرون
منشور في: (2021-02-01)

Reactivity of aniline nucleophilic centers in reaction with formaldehyde
حسب: V. V. Bochkarev, وآخرون
منشور في: (2009-06-01)

Reactivity of aniline nucleophilic centers in reaction with formaldehyde
حسب: V. V. Bochkarev, وآخرون
منشور في: (2009-06-01)

Synthetic Approaches to Piperazine-Containing Drugs Approved by FDA in the Period of 2011–2023
حسب: Maria Novella Romanelli, وآخرون
منشور في: (2023-12-01)

Reaction-Based Amine and Alcohol Gases Detection with Triazine Ionic Liquid Materials
حسب: Hsin-Yi Li, وآخرون
منشور في: (2019-12-01)

Products of chemical reactions that occur during high-temperature heat treatment of the meat products
حسب: D. A. Utyanov, وآخرون
منشور في: (2019-12-01)

Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as <i>β</i>-Glucuronidase Inhibitors: In Vitro and In Silico Studies
حسب: Sarosh Iqbal, وآخرون
منشور في: (2022-11-01)

2,4-Dichloropyrimidine
حسب: Yan Chen, وآخرون
منشور في: (2009-06-01)

Green approach for the synthesis of some new α, β-unsaturated ketimines under water suspension
حسب: Subash M. Lonkar, وآخرون
منشور في: (2012-02-01)

Addition reactions /
حسب: 291289 Boyd, G. V.

Direct Amination of Nitroquinoline Derivatives via Nucleophilic Displacement of Aromatic Hydrogen
حسب: Jakub Wantulok, وآخرون
منشور في: (2021-03-01)

New insight into the effect of hydroxyl substituted flavonoids on the cytotoxicity of 2‐amino‐3‐methylimidazo[4,5‐f]quinoline
حسب: Hongting Deng, وآخرون
منشور في: (2023-03-01)

Evaluation of local spices and herbs as marinating ingredients for the reduction of heterocyclic amines in grilled beef
حسب: Sepahpour, Shabnam
منشور في: (2017)

Effect Of Cooking Methods And Conditions On Heterocyclic Amines Content In Satay And Roasted Marinated Chicken
حسب: Mohd Mukhtar, Mohd Safzan
منشور في: (2009)

Study of the Aniline removal from industrial wastewater by Electrochemical process
حسب: M Arqiani, وآخرون
منشور في: (2013-05-01)

Formation of MeIQx and PhIP in model matrices from amino acids, carbohydrates, and creatine
حسب: D. A. Utyanov, وآخرون
منشور في: (2024-07-01)

Synthesis of <i>Meso</i>-Diarylaminocorroles via S<sub>N</sub>Ar Reactions
حسب: Kento Ueta, وآخرون
منشور في: (2019-02-01)

Synthesis of 3-Aroyl-4-heteroarylpyrrole Derivatives by the Van Leusen Method
حسب: Jorge Trilleras, وآخرون
منشور في: (2022-02-01)

Flavouring Group Evaluation 86, (FGE.86) ‐ Consideration of aliphatic and aromatic amines and amides evaluated by JECFA (65th meeting) ‐ Scientific Opinion of the Panel on Food Additives ‐ Flavourings, Processing Aids and Materials in Contact with Food
حسب: European Food Safety Authority (EFSA)
منشور في: (2008-11-01)

Synthesis, Crystal Structure, Herbicide Safening, and Antifungal Activity of N-(4,6-Dichloropyrimidine-2-Yl)Benzamide
حسب: Wen-Na Zheng, وآخرون
منشور في: (2018-02-01)

Investigation of the dose and structure effects of lipid oxidation products aldehydes on the generation of heterocyclic amines: A case study of 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP)
حسب: Mantong Zhao, وآخرون
منشور في: (2025-01-01)

A novel synthesis of highly stable palladium nanoparticles and their application in the reduction of nitroaromatic compounds
حسب: Fuad Othman Abdullah, وآخرون
منشور في: (2021-01-01)

Nitração aromática: substituição eletrofílica ou reação com transferência de elétrons? Aromatic nitration: electrophilic substitution or reaction with electron transfer?
حسب: Sheila Pressentin Cardoso, وآخرون
منشور في: (2001-06-01)

Reactions of Tetracyanoethylene with Aliphatic and Aromatic Amines and Hydrazines and Chemical Transformations of Tetracyanoethylene Derivatives
حسب: Elizaveta Ivanova, وآخرون
منشور في: (2024-10-01)

A Molecular Electron Density Theory Study of the Domino Reaction of <i>N</i>-Phenyl Iminoboranes with Benzaldehyde Yielding Fused Bicyclic Compounds
حسب: Luis R. Domingo, وآخرون
منشور في: (2023-08-01)

Aromatic substitution by free radicals, carbenes and nitrenes in aromatic hateroaromatic chemistry
حسب: Challand, Richard, 1946-
منشور في: (1975)

Electrophilic aromatic substitution /
حسب: 290666 Taylor, R.
منشور في: (1990)

A facile synthesis of functionalized 7,8-diaza[5]helicenes through an oxidative ring-closure of 1,1’-binaphthalene-2,2’-diamines (BINAMs)
حسب: Youhei Takeda, وآخرون
منشور في: (2015-01-01)

Perhalogenated pyrimidine scaffolds. Reactions of 5-chloro-2,4,6-trifluoropyrimidine with nitrogen centred nucleophiles
حسب: Emma L. Parks, وآخرون
منشور في: (2008-07-01)

Simple, Practical and Eco-friendly Reduction of Nitroarenes with Zinc in the Presence of olyethylene Glycol Immobilized on Silica Gel as a New Solid–liquid Phase Transfer Catalyst in Water
حسب: Ali Reza Kiasat, وآخرون
منشور في: (2011-06-01)

Comparative Review for Enhancing CO<sub>2</sub> Capture Efficiency with Mixed Amine Systems and Catalysts
حسب: Wenhao Jiang, وآخرون
منشور في: (2024-09-01)

On the Aromaticity and <sup>13</sup>C-NMR Pattern of Pentagonal-Pyramidal Hexamethylbenzene Dication [C<sub>6</sub>(CH<sub>3</sub>)<sub>6</sub>]<sup>2+</sup>: A {C<sub>5</sub>(CH<sub>3</sub>)<sub>5</sub>}<sup>−</sup>–{CCH<sub>3</sub>}<sup>3+</sup> Aggregate
حسب: Desmond MacLeod-Carey, وآخرون
منشور في: (2021-11-01)