A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine
Background: The purpose of this study was to examine the dimensional change of IVC during acute hemorrhage through a volume-controlled acute hemorrhagic shock model in swine. Methods: Volume-controlled hemorrhage was performed in 10 adult Bama mini pigs. Enhanced CT scan and hemodynamic monitoring w...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-09-01
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| Series: | Journal of Investigative Surgery |
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| Online Access: | http://dx.doi.org/10.1080/08941939.2019.1567873 |
| _version_ | 1797684667100430336 |
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| author | Yang Li Hai-feng Qi Le-tian Zhang Wei-guo Zhang Lian-yang Zhang |
| author_facet | Yang Li Hai-feng Qi Le-tian Zhang Wei-guo Zhang Lian-yang Zhang |
| author_sort | Yang Li |
| collection | DOAJ |
| description | Background: The purpose of this study was to examine the dimensional change of IVC during acute hemorrhage through a volume-controlled acute hemorrhagic shock model in swine. Methods: Volume-controlled hemorrhage was performed in 10 adult Bama mini pigs. Enhanced CT scan and hemodynamic monitoring were performed when the cumulative blood loss volume reached 0%, 10%, 20%, 30%, and 40%. The transverse diameter (T) and anteroposterior diameter (AP) of IVC were measured in axial images. Hemodynamic parameters were obtained with Pulse Contour Cardiac Output (PiCCO) hemodynamic monitor device. Arterial blood samples were also collected for artery blood gas analysis at each time point. Results: As the blood loss volume increased, the collapsibility (T/AP) and cross section area (CSA) of IVC significantly changed first in hepatic level and pre-renal level. The significant decrease of the CSA of IVC (shrink) occurred early when the blood loss volume reached only 10%, but the collapse of IVC occurred until the blood loss volume reached 30%. Conclusions: IVC shrank early but collapsed late during the acute hemorrhage in swine. The finding of collapsed IVC on CT scans suggested severe hypovolemic shock. Evaluation of the IVC at the CT scans can be an adjunctive test of the hemodynamic status in trauma patients. |
| first_indexed | 2024-03-12T00:34:03Z |
| format | Article |
| id | doaj.art-51eb1d6d66484de2943d2bbd039bc7e9 |
| institution | Directory Open Access Journal |
| issn | 0894-1939 1521-0553 |
| language | English |
| last_indexed | 2024-03-12T00:34:03Z |
| publishDate | 2020-09-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Investigative Surgery |
| spelling | doaj.art-51eb1d6d66484de2943d2bbd039bc7e92023-09-15T10:07:29ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532020-09-0133869169810.1080/08941939.2019.15678731567873A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in SwineYang Li0Hai-feng Qi1Le-tian Zhang2Wei-guo Zhang3Lian-yang Zhang4Institute of Surgery Research, Daping Hospital, Army Medical UniversityInstitute of Surgery Research, Daping Hospital, Army Medical UniversityInstitute of Surgery Research, Daping Hospital, Army Medical UniversityInstitute of Surgery Research, Daping Hospital, Army Medical UniversityInstitute of Surgery Research, Daping Hospital, Army Medical UniversityBackground: The purpose of this study was to examine the dimensional change of IVC during acute hemorrhage through a volume-controlled acute hemorrhagic shock model in swine. Methods: Volume-controlled hemorrhage was performed in 10 adult Bama mini pigs. Enhanced CT scan and hemodynamic monitoring were performed when the cumulative blood loss volume reached 0%, 10%, 20%, 30%, and 40%. The transverse diameter (T) and anteroposterior diameter (AP) of IVC were measured in axial images. Hemodynamic parameters were obtained with Pulse Contour Cardiac Output (PiCCO) hemodynamic monitor device. Arterial blood samples were also collected for artery blood gas analysis at each time point. Results: As the blood loss volume increased, the collapsibility (T/AP) and cross section area (CSA) of IVC significantly changed first in hepatic level and pre-renal level. The significant decrease of the CSA of IVC (shrink) occurred early when the blood loss volume reached only 10%, but the collapse of IVC occurred until the blood loss volume reached 30%. Conclusions: IVC shrank early but collapsed late during the acute hemorrhage in swine. The finding of collapsed IVC on CT scans suggested severe hypovolemic shock. Evaluation of the IVC at the CT scans can be an adjunctive test of the hemodynamic status in trauma patients.http://dx.doi.org/10.1080/08941939.2019.1567873hemorrhagic shockcomputed tomographyinferior vena cavaswine model |
| spellingShingle | Yang Li Hai-feng Qi Le-tian Zhang Wei-guo Zhang Lian-yang Zhang A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine Journal of Investigative Surgery hemorrhagic shock computed tomography inferior vena cava swine model |
| title | A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine |
| title_full | A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine |
| title_fullStr | A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine |
| title_full_unstemmed | A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine |
| title_short | A Quantitative Study of the Dimensional Change of Inferior Vena Cava on Computed Tomography During Acute Hemorrhage Shock in Swine |
| title_sort | quantitative study of the dimensional change of inferior vena cava on computed tomography during acute hemorrhage shock in swine |
| topic | hemorrhagic shock computed tomography inferior vena cava swine model |
| url | http://dx.doi.org/10.1080/08941939.2019.1567873 |
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