Evaluation of N-benzoylthiourea derivatives as possible analgesic agents by predicting their physicochemical and pharmacokinetic properties, toxicity, and analgesic activity

Evaluation of N-benzoylthiourea derivatives as possible analgesic agents by predicting their physicochemical and pharmacokinetic properties, toxicity, and analgesic activity

This study aimed to predict the physicochemical properties, pharmacokinetic properties (ADME), toxicity, and analgesic activity of 30 compounds of N-benzoylthiourea derivatives that are potential analgesic drugs. One of the mechanisms of action of N-benzoylthiourea derivatives is the inhibition of t...

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Bibliographic Details
Main Authors: Suko Hardjono, Siswandono Siswandono, Rina Andayani
Format: Article
Language:English
Published: Universitas Gadjah Mada, Yogyakarta 2018-02-01
Series:Indonesian Journal of Biotechnology
Subjects:
ADME
analgesic activity
molecular modeling
N-benzoylthiourea
toxicity
Online Access:https://jurnal.ugm.ac.id/ijbiotech/article/view/27171

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