The structure of a tetrameric septin complex reveals a hydrophobic element essential for NC-interface integrity

Abstract The septins of the yeast Saccharomyces cerevisiae assemble into hetero-octameric rods by alternating interactions between neighboring G-domains or N- and C-termini, respectively. These rods polymerize end to end into apolar filaments, forming a ring beneath the prospective new bud that expa...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Benjamin Grupp, Lukas Denkhaus, Stefan Gerhardt, Matthis Vögele, Nils Johnsson, Thomas Gronemeyer
Format: Artikel
Sprache:English
Veröffentlicht: Nature Portfolio 2024-01-01
Schriftenreihe:Communications Biology
Online Zugang:https://doi.org/10.1038/s42003-023-05734-w