Perspectives on the treatment of the longitudinal spinal cord injury

Abstract The current technique for surgical treatment of the longitudinal spinal cord injury has proven to be successful for restoration of some motor function and alleviation of pain. This has been the first step in finding a cure for spinal cord injuries, but so far there are many obstacles still...

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Main Author: Thomas Carlstedt
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-07-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2010.00011/full
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author Thomas Carlstedt
author_facet Thomas Carlstedt
author_sort Thomas Carlstedt
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description Abstract The current technique for surgical treatment of the longitudinal spinal cord injury has proven to be successful for restoration of some motor function and alleviation of pain. This has been the first step in finding a cure for spinal cord injuries, but so far there are many obstacles still to be overcome. In this particular injury return of function from spinal cord surgery is only partial. Some of the main remaining problems are related to injury induced neuronal death, direction and specificity of regeneration and muscle and receptor disintegration from long time denervation. Currently this is a surgical procedure without any adjuvant treatments. In order to gain further functional improvement combinational therapies developed in basic science experiments are essential.
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spelling doaj.art-51f8eb21e41b4170bc6c480d117d67aa2022-12-22T01:14:52ZengFrontiers Media S.A.Frontiers in Neurology1664-22952010-07-01110.3389/fneur.2010.000111631Perspectives on the treatment of the longitudinal spinal cord injuryThomas Carlstedt0Karolinska Institute, SödersjukhusetAbstract The current technique for surgical treatment of the longitudinal spinal cord injury has proven to be successful for restoration of some motor function and alleviation of pain. This has been the first step in finding a cure for spinal cord injuries, but so far there are many obstacles still to be overcome. In this particular injury return of function from spinal cord surgery is only partial. Some of the main remaining problems are related to injury induced neuronal death, direction and specificity of regeneration and muscle and receptor disintegration from long time denervation. Currently this is a surgical procedure without any adjuvant treatments. In order to gain further functional improvement combinational therapies developed in basic science experiments are essential.http://journal.frontiersin.org/Journal/10.3389/fneur.2010.00011/fullspinal cord injuryfunctional recoverynerve plexusroot avulsionspinal cord surgery
spellingShingle Thomas Carlstedt
Perspectives on the treatment of the longitudinal spinal cord injury
Frontiers in Neurology
spinal cord injury
functional recovery
nerve plexus
root avulsion
spinal cord surgery
title Perspectives on the treatment of the longitudinal spinal cord injury
title_full Perspectives on the treatment of the longitudinal spinal cord injury
title_fullStr Perspectives on the treatment of the longitudinal spinal cord injury
title_full_unstemmed Perspectives on the treatment of the longitudinal spinal cord injury
title_short Perspectives on the treatment of the longitudinal spinal cord injury
title_sort perspectives on the treatment of the longitudinal spinal cord injury
topic spinal cord injury
functional recovery
nerve plexus
root avulsion
spinal cord surgery
url http://journal.frontiersin.org/Journal/10.3389/fneur.2010.00011/full
work_keys_str_mv AT thomascarlstedt perspectivesonthetreatmentofthelongitudinalspinalcordinjury