Recombinant canine basic fibroblast growth factor-induced differentiation of canine bone marrow mesenchymal stem cells into voltage- and glutamate-responsive neuron-like cells

Recombinant canine basic fibroblast growth factor-induced differentiation of canine bone marrow mesenchymal stem cells into voltage- and glutamate-responsive neuron-like cells

Introduction: Basic fibroblast growth factor (bFGF) is a promising cytokine in regenerative therapy for spinal cord injury. In this study, recombinant canine bFGF (rc-bFGF) was synthesized for clinical use in dogs, and the ability of rc-bFGF to differentiate canine bone marrow mesenchymal stem cells...

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Bibliographic Details
Main Authors: Kazuya Edamura, Yusuke Takahashi, Airi Fujii, Yoshikazu Masuhiro, Takanori Narita, Mamiko Seki, Kazushi Asano
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
Basic fibroblast growth factor
Bone marrow
Dog
Differentiation
Neuron
Mesenchymal stem cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300638

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