PFAS Modulate Osmotic Signaling Independent of Gravimetric Changes in the Rat Uterus

PFAS Modulate Osmotic Signaling Independent of Gravimetric Changes in the Rat Uterus

Various PFAS have been identified as potential endocrine-disrupting chemicals due to estrogen receptor activation, impacts on puberty timing, or impacts on hormonally sensitive endpoints in fish. This study screened multiple PFAS in the rat uterotrophic assay to determine potential estrogenic effect...

Full description

Bibliographic Details
Main Authors:	Aaron Dixon, Evelyn G. Rowan, Allison N. Yackley, Erin P. Hines
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	Toxics
Subjects:	PFAS uterus reproductive toxicology endocrine disruptors cancer signaling
Online Access:	https://www.mdpi.com/2305-6304/12/3/170

Similar Items

Editorial: Emerging Chemical Risks for Human Health: Endocrine Disruption by Per- and Poly-Fluorinated Alkyl Substances (PFAS)
by: Andrea Di Nisio, et al.
Published: (2022-01-01)

Endocrine disruption by PFAS: A major concern associated with legacy and replacement substances
by: Panieri Emiliano, et al.
Published: (2021-01-01)

The PFAS-Tox Database: A systematic evidence map of health studies on 29 per- and polyfluoroalkyl substances
by: Katherine E. Pelch, et al.
Published: (2022-09-01)

Early Warnings by Liver Organoids on Short- and Long-Chain PFAS Toxicity
by: Stefano Palazzolo, et al.
Published: (2022-02-01)

Ancaman kepupusan : masa depan manusia tergugat akibat bahan-bahan Kimia Pengganggu Hormon (EDCs)/
by: Persatuan Pengguna Pulau Pinang
Published: (2000)

Multi- and Transgenerational Effects of Developmental Exposure to Environmental Levels of PFAS and PFAS Mixture in Zebrafish (<i>Danio rerio</i>)
by: Alex Haimbaugh, et al.
Published: (2022-06-01)

Endocrine-disrupting substances: I. Relative risks of PFAS in drinking water
by: Francisco Alberto Tomei Torres, et al.
Published: (2023-04-01)

Maternal consumption of ultra-processed foods and newborn exposure to perfluoroalkyl substances (PFAS)
by: Nathalia Ferrazzo Naspolini, et al.
Published: (2021-12-01)

Impact of Environmental Pollution on Female Reproduction
by: Mosammat Rashida Begum, et al.
Published: (2022-06-01)

An Overview of Per- and Polyfluoroalkyl Substances (PFAS) in the Environment: Source, Fate, Risk and Regulations
by: Ziyad Abunada, et al.
Published: (2020-12-01)

Influence of Area, Age and Sex on Per- and Polyfluorinated Alkyl Substances Detected in Roe Deer Muscle and Liver from Selected Areas of Northern Italy
by: Susanna Draghi, et al.
Published: (2024-02-01)

A comprehensive review on the need for integrated strategies and process modifications for per- and polyfluoroalkyl substances (PFAS) removal: Current insights and future prospects
by: Neha Sharma, et al.
Published: (2024-06-01)

Diethylstilbestrol Action on Leydig Cell Function and Testicular Descent
by: Christopher R. Cederroth, et al.
Published: (2008-05-01)

Editorial: Endocrine disruptors affecting the human and companion animal endocrine functions – similarities and indicators in ONE Health concept
by: Julianna Thuróczy
Published: (2023-10-01)

There’s Something in What We Eat: An Overview on the Extraction Techniques and Chromatographic Analysis for PFAS Identification in Agri-Food Products
by: Alessia Iannone, et al.
Published: (2024-04-01)

Glyphosate Interference in Follicular Organization in the Wall Lizard <i>Podarcis siculus</i>
by: Luigi Rosati, et al.
Published: (2023-04-01)

Geographical characteristics that promote persistence and accumulation of PFAS in coastal waters and open seas: Current and emerging hot spots
by: Berrin Tansel
Published: (2024-01-01)

Sources, Fate, and Detection of Dust-Associated Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS): A Review
by: Usman M. Ismail, et al.
Published: (2023-03-01)

Editorial: Endocrine disruptors: mechanism of action and implications for human health
by: Giulia Gaggi, et al.
Published: (2024-02-01)

Editorial: Endocrine-Disrupting Compounds in Plastics and Their Effects on Reproduction, Fertility, and Development
by: Francesca Maradonna, et al.
Published: (2022-03-01)

Developmental and Reproductive Outcomes in Male Rats Exposed to Triclosan: Two-Generation Study
by: Bruno Garcia Montagnini, et al.
Published: (2021-10-01)

Rationale for the study of the human sex ratio in population studies of polluted environments
by: Jarrell John
Published: (2002-01-01)

Introduction
by: Felix R. Althaus
Published: (2008-05-01)

Assembly and Curation of Lists of Per- and Polyfluoroalkyl Substances (PFAS) to Support Environmental Science Research
by: Antony J. Williams, et al.
Published: (2022-04-01)

Overview of Per- and Polyfluoroalkyl Substances (PFAS), Their Applications, Sources, and Potential Impacts on Human Health
by: Zunaira Habib, et al.
Published: (2024-03-01)

Review of per- and polyfluoroalkyl substances (PFAS) bioaccumulation in earthworms
by: Lawrence P. Burkhard, et al.
Published: (2023-04-01)

PFAS in the Drinking Water Source: Analysis of the Contamination Levels, Origin and Emission Rates
by: Dauren Mussabek, et al.
Published: (2022-12-01)

Endocrine Disruptor Compounds in Environment: Focus on Women’s Reproductive Health and Endometriosis
by: Livia Interdonato, et al.
Published: (2023-03-01)

Endocrine-Disrupting Chemicals, Gut Microbiota, and Human (In)Fertility—It Is Time to Consider the Triad
by: Gemma Fabozzi, et al.
Published: (2022-10-01)

Reproductive Toxicity Induced by Low Dose Bisphenol A(BPA) in Male Rats
by: Sara Hatem Mohamed Fawzy Elshafiey, et al.
Published: (2020-12-01)

On the rumors about the silent spring: review of the scientific evidence linking occupational and environmental pesticide exposure to endocrine disruption health effects
by: Pierluigi Cocco

Perinatal Exposure to Methoxychlor Affects Reproductive Function and Sexual Behavior in Mice
by: Mariangela Martini, et al.
Published: (2020-09-01)

Estrogenic Pastures: A Source of Endocrine Disruption in Sheep Reproduction
by: Kelsey R. Pool, et al.
Published: (2022-04-01)

Transient exposure to environmentally realistic concentrations of di-(2-ethylhexyl)-phthalate during sensitive windows of development impaired larval survival and reproduction success in Japanese medaka
by: Bonny Bun Ho Yuen, et al.
Published: (2020-01-01)

On the rumors about the silent spring: review of the scientific evidence linking occupational and environmental pesticide exposure to endocrine disruption health effects
by: Cocco Pierluigi
Published: (2002-01-01)

Comparative Evaluation of the Effects of Legacy and New Generation Perfluoralkyl Substances (PFAS) on Thyroid Cells In Vitro
by: Luca De Toni, et al.
Published: (2022-06-01)

Rafting on the Evidence for Lipid Raft-like Domains as Hubs Triggering Environmental Toxicants’ Cellular Effects
by: Dorinda Marques-da-Silva, et al.
Published: (2023-09-01)

Integrative Strategy of Testing Systems for Identification of Endocrine Disruptors Inducing Metabolic Disorders—An Introduction to the OBERON Project
by: Karine Audouze, et al.
Published: (2020-04-01)

Endocrine disrupting chemicals and COVID-19 relationships: A computational systems biology approach
by: Qier Wu, et al.
Published: (2021-12-01)

Perfluoroalkyl Substances (PFAS) Affect Inflammation in Lung Cells and Tissues
by: Julie Dragon, et al.
Published: (2023-05-01)