Severe and refractory hypotension after intentional minoxidil overdose: a case report

AbstractWe describe a case of minoxidil overdose which led to a prolonged distributive shock. Although this was a case of combined trauma presenting with self-inflicted lacerations and intentional overdose via ingestion of minoxidil-finasteride topical spray and non-steroidal anti-inflammatory drugs...

Full description

Bibliographic Details
Main Authors: Mir Mazhar, Adrian Estrada, Alexander Zorn, Robert V. Madlinger, Maurizio Miglietta
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Toxicology Communications
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/24734306.2023.2293403
Description
Summary:AbstractWe describe a case of minoxidil overdose which led to a prolonged distributive shock. Although this was a case of combined trauma presenting with self-inflicted lacerations and intentional overdose via ingestion of minoxidil-finasteride topical spray and non-steroidal anti-inflammatory drugs (NSAIDs), we believe the hypotension encountered was due to minoxidil’s effects and not exsanguination. In conjunction with poison control, our patient was successfully managed with phenylephrine, vasopressin, midodrine, and several liters of IV hydration despite prolonged refractory hypotension.
ISSN:2473-4306