TGF-β Targeted by miR-27a Modulates Anti-Parasite Responses of Immune System
Background: Immune cells and their secreted cytokines are known as the first barrier against pathogens. Leishmania major as an intracellular protozoan produces anti-inflammatory cytokines that lead to proliferation and survival of the parasite in the macrophages. miRNAs are small non-coding RNA mol...
Main Authors: | Faezeh Hamidi, Samira Mohammadi -Yeganeh, Mostafa Haji Molla Hoseini, Seyyed Javad Seyyed Tabaei, Niloofar Taghipour, Ameneh Koochaki, Vahedeh Hosseini, Ali Haghighi |
---|---|
Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2023-09-01
|
Series: | Iranian Journal of Parasitology |
Subjects: | |
Online Access: | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/3696 |
Similar Items
-
Comparative Expression Profile Analysis of Apoptosis-Related miRNA and Its Target Gene in Leishmania major Infected Macrophages
by: Zohreh LASJERDI, et al.
Published: (2020-09-01) -
ITS2-rDNA fragments of Leishmania species isolated from the great gerbil in Iran, 2021
by: Maryam Shirazian, et al.
Published: (2023-03-01) -
Neutrophil extracellular traps formation: effect of Leishmania major promastigotes and salivary gland homogenates of Phlebotomus papatasi in human neutrophil culture
by: Fahimeh Firouzjaie, et al.
Published: (2024-04-01) -
Super Infection of Cutaneous Leishmaniasis Caused by Leishmania major and L. tropica to Crithidia fasciculata in Shiraz, Iran
by: Aliyar MIRZAPOUR, et al.
Published: (2019-12-01) -
Effect of Leishmania major Infection on the Expression of TGF Beta in Murine
by: F Al-Muhsin Al-Khayat, et al.
Published: (2021-11-01)