Network Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose Glucocorticoids in Anti-rheumatoid Arthritis

Network Pharmacology Based Research on the Combination Mechanism Between Escin and Low Dose Glucocorticoids in Anti-rheumatoid Arthritis

Rheumatoid arthritis (RA) is characterized by chronic progressive symmetrical synovitis and destruction of multiple joints. Glucocorticoids (GCs) are widely used in the treatment of RA. However, their adverse effects can be serious. Escin, which is isolated from Aesculus hippocastanum L., has been r...

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Bibliographic Details
Main Authors: Leiming Zhang, Yanan Huang, Chuanhong Wu, Yuan Du, Peng Li, Meiling Wang, Xinlin Wang, Yanfang Wang, Yanfei Hao, Tian Wang, Baofeng Fan, Zhuye Gao, Fenghua Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
glucocorticoids
glucocorticoid receptor
Escin
dexamethasone
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00280/full

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