Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010
The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioido...
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2012-12-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/18/12/12-0638_article |
| _version_ | 1828836585720774656 |
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| author | Rebecca Lipsitz Susan Garges Rosemarie Aurigemma Prasith Baccam David D. Blaney Allen C. Cheng Bart J. Currie David Dance Jay E. Gee Joseph Larsen Direk Limmathurotsakul Meredith G. Morrow Robert Norton Elizabeth O’Mara Sharon J. Peacock Nicki Pesik L. Paige Rogers Herbert P. Schweizer Ivo Steinmetz Gladys Tan Patrick Tan W. Joost Wiersinga Vanaporn Wuthiekanun Theresa L. Smith |
| author_facet | Rebecca Lipsitz Susan Garges Rosemarie Aurigemma Prasith Baccam David D. Blaney Allen C. Cheng Bart J. Currie David Dance Jay E. Gee Joseph Larsen Direk Limmathurotsakul Meredith G. Morrow Robert Norton Elizabeth O’Mara Sharon J. Peacock Nicki Pesik L. Paige Rogers Herbert P. Schweizer Ivo Steinmetz Gladys Tan Patrick Tan W. Joost Wiersinga Vanaporn Wuthiekanun Theresa L. Smith |
| author_sort | Rebecca Lipsitz |
| collection | DOAJ |
| description | The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options. |
| first_indexed | 2024-12-12T18:24:09Z |
| format | Article |
| id | doaj.art-5202ba97436b4303bc57bfb60f85d843 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-12T18:24:09Z |
| publishDate | 2012-12-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-5202ba97436b4303bc57bfb60f85d8432022-12-22T00:16:04ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592012-12-01181210.3201/eid1812.120638Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010Rebecca LipsitzSusan GargesRosemarie AurigemmaPrasith BaccamDavid D. BlaneyAllen C. ChengBart J. CurrieDavid DanceJay E. GeeJoseph LarsenDirek LimmathurotsakulMeredith G. MorrowRobert NortonElizabeth O’MaraSharon J. PeacockNicki PesikL. Paige RogersHerbert P. SchweizerIvo SteinmetzGladys TanPatrick TanW. Joost WiersingaVanaporn WuthiekanunTheresa L. SmithThe US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options.https://wwwnc.cdc.gov/eid/article/18/12/12-0638_articleBurkholderia pseudomalleimelioidosisBurkholderia malleiglandersdrug therapypostexposure prophylaxis |
| spellingShingle | Rebecca Lipsitz Susan Garges Rosemarie Aurigemma Prasith Baccam David D. Blaney Allen C. Cheng Bart J. Currie David Dance Jay E. Gee Joseph Larsen Direk Limmathurotsakul Meredith G. Morrow Robert Norton Elizabeth O’Mara Sharon J. Peacock Nicki Pesik L. Paige Rogers Herbert P. Schweizer Ivo Steinmetz Gladys Tan Patrick Tan W. Joost Wiersinga Vanaporn Wuthiekanun Theresa L. Smith Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 Emerging Infectious Diseases Burkholderia pseudomallei melioidosis Burkholderia mallei glanders drug therapy postexposure prophylaxis |
| title | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
| title_full | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
| title_fullStr | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
| title_full_unstemmed | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
| title_short | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
| title_sort | workshop on treatment of and postexposure prophylaxis for burkholderia pseudomallei and b mallei infection 2010 |
| topic | Burkholderia pseudomallei melioidosis Burkholderia mallei glanders drug therapy postexposure prophylaxis |
| url | https://wwwnc.cdc.gov/eid/article/18/12/12-0638_article |
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