Presentations associated with porphyrias in intensive care units
Porphyrias are a group of uncommon congenital metabolic diseases that are difficult to diagnose as they often present with nonspecific symptoms, mimicking other diseases. A significant number of patients with porphyrias have been admitted to intensive care units with acute abdominal pain, neuro-psyc...
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| Format: | Article |
| Language: | English |
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Southwest Respiratory and Critical Care Chronicles
2016-10-01
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| Series: | Southwest Respiratory and Critical Care Chronicles |
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| Online Access: | http://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/314 |
| _version_ | 1819103529246130176 |
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| author | Doungporn Ruthirago Parunyou Julayanont Supannee Rassameehiran |
| author_facet | Doungporn Ruthirago Parunyou Julayanont Supannee Rassameehiran |
| author_sort | Doungporn Ruthirago |
| collection | DOAJ |
| description | Porphyrias are a group of uncommon congenital metabolic diseases that are difficult to diagnose as they often present with nonspecific symptoms, mimicking other diseases. A significant number of patients with porphyrias have been admitted to intensive care units with acute abdominal pain, neuro-psychiatric symptoms, or hyponatremia. Due to the nonspecific symptoms, many patients have a delayed diagnosis. Moreover, some patients have received treatments that precipitate acute porphyric attacks, such as antibiotics or antiepileptics, causing worsening of symptoms. This article reviews the various clinical presentations and appropriate treatment of acute porphyrias in the ICU. Early diagnosis and appropriate management are important for preventing long-term disability and achieving good outcomes. |
| first_indexed | 2024-12-22T01:51:54Z |
| format | Article |
| id | doaj.art-52031668769a4d68a566ffd42fc9e312 |
| institution | Directory Open Access Journal |
| issn | 2325-9205 |
| language | English |
| last_indexed | 2024-12-22T01:51:54Z |
| publishDate | 2016-10-01 |
| publisher | Southwest Respiratory and Critical Care Chronicles |
| record_format | Article |
| series | Southwest Respiratory and Critical Care Chronicles |
| spelling | doaj.art-52031668769a4d68a566ffd42fc9e3122022-12-21T18:42:52ZengSouthwest Respiratory and Critical Care ChroniclesSouthwest Respiratory and Critical Care Chronicles2325-92052016-10-014165155276Presentations associated with porphyrias in intensive care unitsDoungporn Ruthirago0Parunyou Julayanont1Supannee RassameehiranDept of Neurology Texas Tech University Health Science Center Lubbock, TXDept of Neurology Texas Tech University Health Science Center Lubbock, TXPorphyrias are a group of uncommon congenital metabolic diseases that are difficult to diagnose as they often present with nonspecific symptoms, mimicking other diseases. A significant number of patients with porphyrias have been admitted to intensive care units with acute abdominal pain, neuro-psychiatric symptoms, or hyponatremia. Due to the nonspecific symptoms, many patients have a delayed diagnosis. Moreover, some patients have received treatments that precipitate acute porphyric attacks, such as antibiotics or antiepileptics, causing worsening of symptoms. This article reviews the various clinical presentations and appropriate treatment of acute porphyrias in the ICU. Early diagnosis and appropriate management are important for preventing long-term disability and achieving good outcomes.http://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/314acute intermittent porphyria, pain, neuropathy, hyponatremia |
| spellingShingle | Doungporn Ruthirago Parunyou Julayanont Supannee Rassameehiran Presentations associated with porphyrias in intensive care units Southwest Respiratory and Critical Care Chronicles acute intermittent porphyria, pain, neuropathy, hyponatremia |
| title | Presentations associated with porphyrias in intensive care units |
| title_full | Presentations associated with porphyrias in intensive care units |
| title_fullStr | Presentations associated with porphyrias in intensive care units |
| title_full_unstemmed | Presentations associated with porphyrias in intensive care units |
| title_short | Presentations associated with porphyrias in intensive care units |
| title_sort | presentations associated with porphyrias in intensive care units |
| topic | acute intermittent porphyria, pain, neuropathy, hyponatremia |
| url | http://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/314 |
| work_keys_str_mv | AT doungpornruthirago presentationsassociatedwithporphyriasinintensivecareunits AT parunyoujulayanont presentationsassociatedwithporphyriasinintensivecareunits AT supanneerassameehiran presentationsassociatedwithporphyriasinintensivecareunits |