The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma

The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma

Host anti-tumor immunity can be hindered by various mechanisms present within the tumor microenvironment, including the actions of myeloid-derived suppressor cells (MDSCs). We investigated the role of the CCR2/MCP-1 pathway in MDSC-associated tumor progression in murine lung cancer models. Phenotypi...

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Bibliographic Details
Main Authors: Payal Mittal, Liqing Wang, Tatiana Akimova, Craig A. Leach, Jose C. Clemente, Matthew R. Sender, Yao Chen, Brandon J. Turunen, Wayne W. Hancock
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
MDSC
CCR2
lung cancer
anti-tumor immunity
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/12/12/3723

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