Screening and identification of broadly neutralizing antibodies against different mutant strains of SARS-CoV2

Screening and identification of broadly neutralizing antibodies against different mutant strains of SARS-CoV2

Objective To screen high-affinity neutralizing antibodies with broad spectrum specificity against different SARS-CoV2 mutants and verify their functions. Methods Balb/c mice were immunized twice with SARS-CoV2 S protein mRNA vaccine coated with liposome, and the specific antibody content in serum wa...

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Bibliographic Details
Main Author:	TONG Ke-xin, CAI Meng-hua, HE Wei, ZHANG Jian-min
Format:	Article
Language:	zho
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-05-01
Series:	Jichu yixue yu linchuang
Subjects:	severe acute respiratory syndrome coronavirus 2(sars-cov2)\|hybridoma cells\|broadly neutralizing antibody
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-5-752.pdf

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