Genetic Variant Overlap Analysis Identifies Established and Putative Genes Involved in Pulmonary Fibrosis

Genetic Variant Overlap Analysis Identifies Established and Putative Genes Involved in Pulmonary Fibrosis

In only around 40% of families with pulmonary fibrosis (PF) a suspected genetic cause can be found. Genetic overlap analysis of Whole Exome Sequencing (WES) data may be a powerful tool to discover new shared variants in novel genes for PF. As a proof of principle, we first selected unrelated PF pati...

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Bibliographic Details
Main Authors: Karlijn Groen, Joanne J. van der Vis, Aernoud A. van Batenburg, Karin M. Kazemier, Jan C. Grutters, Coline H. M. van Moorsel
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
idiopathic pulmonary fibrosis
genetics
telomeres
<i>TDP1</i>
<i>TOM1L2</i>
Online Access:https://www.mdpi.com/1422-0067/24/3/2790

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