A cross-sectional study on the association of single nucleotide polymorphism of leptin receptor (Gln223Arg) and insulin resistance in gestational diabetes mellitus

A cross-sectional study on the association of single nucleotide polymorphism of leptin receptor (Gln223Arg) and insulin resistance in gestational diabetes mellitus

Background: The role of genetics in pathophysiology of gestational diabetes mellitus (GDM) is least explored. Objective of the study is to find the association of leptin receptor (LEPR) gene polymorphism with GDM and its role in altered leptin levels, insulin resistance, and dyslipidemia in GDM. Met...

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Bibliographic Details
Main Authors: Usha Adiga, Sachidananda Adiga, P.B. Nandit, Lakshmi Manjeera, Aparna Rao, Abdul-Kareem Mohammed Ghilan, Atif Abdulwahab A. Oyouni, Yousef M. Hawsawi, Abdulrahman Theyab, Mohammad Algahtani, Othman R. Alzahrani, Ravi Mundugaru
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of King Saud University: Science
Subjects:
Gestational diabetes mellitus
Insulin resistance
Hardy-weinberg equillibrium
Leptin
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364721003244

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