Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in <italic>ex vivo</italic> Guinea Pig Hearts and Its Alteration During Ischemia and Reperfusion

Optical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in <italic>ex vivo</italic> Guinea Pig Hearts and Its Alteration During Ischemia and Reperfusion

Oxidation of substrates to generate ATP in mitochondria is mediated by redox reactions of NADH and FADH2. Cardiac ischemia and reperfusion (IR) injury compromises mitochondrial oxidative phosphorylation. We hypothesize that IR alters the metabolic heterogeneity of mitochondrial redox state of the he...

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Bibliographic Details
Main Authors:	Mahsa Ranji, Mohammad Masoudi Motlagh, Fahimeh Salehpour, Reyhaneh Sepehr, James S. Heisner, Ranjan K. Dash, Amadou K. S. Camara
Format:	Article
Language:	English
Published:	IEEE 2016-01-01
Series:	IEEE Journal of Translational Engineering in Health and Medicine
Subjects:	Optical cryoimaging mitochondria ischemia and reperfusion redox state metabolism
Online Access:	https://ieeexplore.ieee.org/document/7492206/

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