Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial

Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial

Objective: The osteoporosis drug strontium ranelate dissociates bone remodelling processes. It also inhibits subchondral bone resorption and stimulates cartilage matrix formation in vitro. Exploratory studies in the osteoporosis trialsreport that strontium ranelate reduces biomarkers of cartilage de...

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Bibliographic Details
Main Authors:	Cyrus Cooper, J-Y Reginster, R Chapurlat, C Christiansen, H Genant, N Bellamy, W Bensen, F Navarro, J Badurski, E Nasonov, X Chevalier, P N Sambrook
Format:	Article
Language:	Russian
Published:	IMA PRESS LLC 2013-12-01
Series:	Научно-практическая ревматология
Subjects:	базисные противовоспалительные препараты ширина суставной щели остеоартроз коленного сустава рентгенограмма колена рандомизированное клиническое исследование стронция ранелат структурно-модифицирующее лечение
Online Access:	https://rsp.mediar-press.net/rsp/article/view/1333

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