γ-Secretase Modulatory Proteins: The Guiding Hand Behind the Running Scissors

Described as the “proteasome of the membrane” or the “scissors in the membrane,” γ-secretase has notoriously complicated biology, and even after decades of research, the full extent of its regulatory mechanism remains unclear. γ-Secretase is an intramembrane aspartyl protease complex composed of fou...

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Bibliographic Details
Main Authors: Eitan Wong, Georgia R. Frost, Yue-Ming Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.614690/full

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