The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction
Purpose: To evaluate the effect of hypothyroidism on erectile function and sperm parameters. Materials and Methods: This study was conducted on 24 patients with hypothyroidism and 66 normal individuals. Serum levels of hormones, including thyroid stimulating hormone (TSH), thyroxin (T4), follicle-st...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences
2012-03-01
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| Series: | Urology Journal |
| Subjects: | |
| Online Access: | http://www.urologyjournal.org/index.php/uj/article/view/1389/634 |
| _version_ | 1818663401018097664 |
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| author | Mohammad Reza Nikoobakht Mehdi Aloosh Nafiseh Nikoobakht Abdolrasoul Mehrsai Farzad Biniaz Mohammad Amin Karjalian |
| author_facet | Mohammad Reza Nikoobakht Mehdi Aloosh Nafiseh Nikoobakht Abdolrasoul Mehrsai Farzad Biniaz Mohammad Amin Karjalian |
| author_sort | Mohammad Reza Nikoobakht |
| collection | DOAJ |
| description | Purpose: To evaluate the effect of hypothyroidism on erectile function and sperm parameters. Materials and Methods: This study was conducted on 24 patients with hypothyroidism and 66 normal individuals. Serum levels of hormones, including thyroid stimulating hormone (TSH), thyroxin (T4), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and testosterone, were measured and semen analysis was done in all the participants. Erectile function was evaluated using International Index of Erectile Function (IIEF-5) questionnaire. Results: The mean IIEF-5 total score was 11.75 [95% confidence interval (CI): 9.70 to 13.79) and 20.81 (95% CI: 20.02 to 21.6) for hypothyroid group and normal subjects, respectively (P = .005). Furthermore, serum concentrations of PRL and seminal parameters were significantly different between two groups (P < .001). Conclusion: Hypothyroidism adversely affects erectile function and sperm parameters, including sperm count, morphology, and motility. In patients with sperm abnormalities and erectile dysfunction, measurement of thyroid hormones is recommended. |
| first_indexed | 2024-12-17T05:16:15Z |
| format | Article |
| id | doaj.art-521a308fe7de42f7b6015c2eba0f3030 |
| institution | Directory Open Access Journal |
| issn | 1735-1308 1735-546X |
| language | English |
| last_indexed | 2024-12-17T05:16:15Z |
| publishDate | 2012-03-01 |
| publisher | Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Urology Journal |
| spelling | doaj.art-521a308fe7de42f7b6015c2eba0f30302022-12-21T22:02:06ZengUrology and Nephrology Research Center, Shahid Beheshti University of Medical SciencesUrology Journal1735-13081735-546X2012-03-0191405409The Role of Hypothyroidism in Male Infertility and Erectile DysfunctionMohammad Reza NikoobakhtMehdi AlooshNafiseh NikoobakhtAbdolrasoul MehrsaiFarzad BiniazMohammad Amin KarjalianPurpose: To evaluate the effect of hypothyroidism on erectile function and sperm parameters. Materials and Methods: This study was conducted on 24 patients with hypothyroidism and 66 normal individuals. Serum levels of hormones, including thyroid stimulating hormone (TSH), thyroxin (T4), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and testosterone, were measured and semen analysis was done in all the participants. Erectile function was evaluated using International Index of Erectile Function (IIEF-5) questionnaire. Results: The mean IIEF-5 total score was 11.75 [95% confidence interval (CI): 9.70 to 13.79) and 20.81 (95% CI: 20.02 to 21.6) for hypothyroid group and normal subjects, respectively (P = .005). Furthermore, serum concentrations of PRL and seminal parameters were significantly different between two groups (P < .001). Conclusion: Hypothyroidism adversely affects erectile function and sperm parameters, including sperm count, morphology, and motility. In patients with sperm abnormalities and erectile dysfunction, measurement of thyroid hormones is recommended.http://www.urologyjournal.org/index.php/uj/article/view/1389/634hypothyroidisminfertilityerectile dysfunctionsemen |
| spellingShingle | Mohammad Reza Nikoobakht Mehdi Aloosh Nafiseh Nikoobakht Abdolrasoul Mehrsai Farzad Biniaz Mohammad Amin Karjalian The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction Urology Journal hypothyroidism infertility erectile dysfunction semen |
| title | The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction |
| title_full | The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction |
| title_fullStr | The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction |
| title_full_unstemmed | The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction |
| title_short | The Role of Hypothyroidism in Male Infertility and Erectile Dysfunction |
| title_sort | role of hypothyroidism in male infertility and erectile dysfunction |
| topic | hypothyroidism infertility erectile dysfunction semen |
| url | http://www.urologyjournal.org/index.php/uj/article/view/1389/634 |
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