Dissecting cellular states of infiltrating microenvironment cells in melanoma by integrating single-cell and bulk transcriptome analysis

Dissecting cellular states of infiltrating microenvironment cells in melanoma by integrating single-cell and bulk transcriptome analysis

Abstract Background Cellular states of different immune cells can affect the activity of the whole immune microenvironment. Methods Here, leveraging reference profiles of microenvironment cell states that were constructed based on single-cell RNA-seq data of melanoma, we dissected the composition of...

Full description

Bibliographic Details
Main Authors: Aiai Shi, Min Yan, Bo Pang, Lin Pang, Yihan Wang, Yujia Lan, Xinxin Zhang, Jinyuan Xu, Yanyan Ping, Jing Hu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Immunology
Subjects:
Cell states
Microenvironment
Immune phenotype
Immunotherapy
Melanoma
Online Access:https://doi.org/10.1186/s12865-023-00587-8

Similar Items

Similar Items