A Fluorinated Analogue of Marine Bisindole Alkaloid 2,2-Bis(6-bromo-1<i>H</i>-indol-3-yl)ethanamine as Potential Anti-Biofilm Agent and Antibiotic Adjuvant Against <i>Staphylococcus aureus</i>

A Fluorinated Analogue of Marine Bisindole Alkaloid 2,2-Bis(6-bromo-1<i>H</i>-indol-3-yl)ethanamine as Potential Anti-Biofilm Agent and Antibiotic Adjuvant Against <i>Staphylococcus aureus</i>

Methicillin resistant <i>Staphylococcus aureus</i> (MRSA) infections represent a major global healthcare problem. Therapeutic options are often limited by the ability of MRSA strains to grow as biofilms on medical devices, where antibiotic persistence and resistance is positively selecte...

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Bibliographic Details
Main Authors: Raffaella Campana, Gianmarco Mangiaterra, Mattia Tiboni, Emanuela Frangipani, Francesca Biavasco, Simone Lucarini, Barbara Citterio
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceuticals
Subjects:
MRSA
marine bisindole alkaloids
antibiofilm activity
adjuvants agents
VBNC cells
Online Access:https://www.mdpi.com/1424-8247/13/9/210

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