A Repertoire of Clinical Non-Dermatophytes Moulds
Humans are constantly exposed to micromycetes, especially filamentous fungi that are ubiquitous in the environment. In the presence of risk factors, mostly related to an alteration of immunity, the non-dermatophyte fungi can then become opportunistic pathogens, causing superficial, deep or dissemina...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/9/4/433 |
| _version_ | 1797604802092335104 |
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| author | Estelle Menu Quentin Filori Jean-Charles Dufour Stéphane Ranque Coralie L’Ollivier |
| author_facet | Estelle Menu Quentin Filori Jean-Charles Dufour Stéphane Ranque Coralie L’Ollivier |
| author_sort | Estelle Menu |
| collection | DOAJ |
| description | Humans are constantly exposed to micromycetes, especially filamentous fungi that are ubiquitous in the environment. In the presence of risk factors, mostly related to an alteration of immunity, the non-dermatophyte fungi can then become opportunistic pathogens, causing superficial, deep or disseminated infections. With new molecular tools applied to medical mycology and revisions in taxonomy, the number of fungi described in humans is rising. Some rare species are emerging, and others more frequent are increasing. The aim of this review is to (i) inventory the filamentous fungi found in humans and (ii) provide details on the anatomical sites where they have been identified and the semiology of infections. Among the 239,890 fungi taxa and corresponding synonyms, if any, retrieved from the Mycobank and NCBI Taxonomy databases, we were able to identify 565 moulds in humans. These filamentous fungi were identified in one or more anatomical sites. From a clinical point of view, this review allows us to realize that some uncommon fungi isolated in non-sterile sites may be involved in invasive infections. It may present a first step in the understanding of the pathogenicity of filamentous fungi and the interpretation of the results obtained with the new molecular diagnostic tools. |
| first_indexed | 2024-03-11T04:51:56Z |
| format | Article |
| id | doaj.art-5221fe1e9b57443a9c1785ee0dfaca76 |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-11T04:51:56Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-5221fe1e9b57443a9c1785ee0dfaca762023-11-17T19:58:04ZengMDPI AGJournal of Fungi2309-608X2023-03-019443310.3390/jof9040433A Repertoire of Clinical Non-Dermatophytes MouldsEstelle Menu0Quentin Filori1Jean-Charles Dufour2Stéphane Ranque3Coralie L’Ollivier4Laboratoire de Parasitologie-Mycologie, IHU Méditerranée Infection, 13385 Marseille, FranceINSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l’Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, FranceINSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l’Information Médicale, ISSPAM, Aix Marseille University, 13385 Marseille, FranceLaboratoire de Parasitologie-Mycologie, IHU Méditerranée Infection, 13385 Marseille, FranceLaboratoire de Parasitologie-Mycologie, IHU Méditerranée Infection, 13385 Marseille, FranceHumans are constantly exposed to micromycetes, especially filamentous fungi that are ubiquitous in the environment. In the presence of risk factors, mostly related to an alteration of immunity, the non-dermatophyte fungi can then become opportunistic pathogens, causing superficial, deep or disseminated infections. With new molecular tools applied to medical mycology and revisions in taxonomy, the number of fungi described in humans is rising. Some rare species are emerging, and others more frequent are increasing. The aim of this review is to (i) inventory the filamentous fungi found in humans and (ii) provide details on the anatomical sites where they have been identified and the semiology of infections. Among the 239,890 fungi taxa and corresponding synonyms, if any, retrieved from the Mycobank and NCBI Taxonomy databases, we were able to identify 565 moulds in humans. These filamentous fungi were identified in one or more anatomical sites. From a clinical point of view, this review allows us to realize that some uncommon fungi isolated in non-sterile sites may be involved in invasive infections. It may present a first step in the understanding of the pathogenicity of filamentous fungi and the interpretation of the results obtained with the new molecular diagnostic tools.https://www.mdpi.com/2309-608X/9/4/433mouldfilamentous fungirepertoire |
| spellingShingle | Estelle Menu Quentin Filori Jean-Charles Dufour Stéphane Ranque Coralie L’Ollivier A Repertoire of Clinical Non-Dermatophytes Moulds Journal of Fungi mould filamentous fungi repertoire |
| title | A Repertoire of Clinical Non-Dermatophytes Moulds |
| title_full | A Repertoire of Clinical Non-Dermatophytes Moulds |
| title_fullStr | A Repertoire of Clinical Non-Dermatophytes Moulds |
| title_full_unstemmed | A Repertoire of Clinical Non-Dermatophytes Moulds |
| title_short | A Repertoire of Clinical Non-Dermatophytes Moulds |
| title_sort | repertoire of clinical non dermatophytes moulds |
| topic | mould filamentous fungi repertoire |
| url | https://www.mdpi.com/2309-608X/9/4/433 |
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