Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal CancerSummary
Background & Aims: The miR-34a gene is a direct target of p53 and is commonly silenced in colorectal cancer (CRC). Here we identified the receptor tyrosine kinase CSF1R as a direct miR-34a target and characterized CSF1R as an effector of p53/miR-34a-mediated CRC suppression. Methods: Analyse...
Main Authors: | Xiaolong Shi, Markus Kaller, Matjaz Rokavec, Thomas Kirchner, David Horst, Heiko Hermeking |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Cellular and Molecular Gastroenterology and Hepatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X20300461 |
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