Synchronous detection of Burkholderia pseudomallei and its ceftazidime resistance mutation based on RNase-HII hydrolysis combined with lateral flow strip assay

Synchronous detection of Burkholderia pseudomallei and its ceftazidime resistance mutation based on RNase-HII hydrolysis combined with lateral flow strip assay

ABSTRACT Melioidosis is a severe and often fatal infectious disease caused by Burkholderia pseudomallei, which poses significant challenges due to its high mortality rate and frequent misdiagnosis. To effectively treat infected patients, especially in epidemic regions like Hainan with a high resista...

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Bibliographic Details
Main Authors: Juan Yao, Zhang Zhang, Shen Tian, Nini Luo, Jun Tan, Yue Zhang, Shuo Gu, Qianfeng Xia
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
melioidosis
Burkholderia pseudomallei
ceftazidime resistance mutation
rhPCR
lateral chromatographic flow strip
universal probes
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01125-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01125-23

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