Physiology and pathology of extracellular vesicules
This year marks the 50th anniversary of the first publication about blood plasma microparticles. Initially considered as cell fragments or “platelet dust”, extracellular vesicles currently attracted the attention of biochemists, biophysicists, physicians, pharmacists around the world. They are heter...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2017-04-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/232 |
| _version_ | 1797855537737498624 |
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| author | M. A. Panteleev A. A. Abaeva D. Yu. Nechipurenko S. I. Obydenniy A. N. Sveshnikova A. M. Shibeko |
| author_facet | M. A. Panteleev A. A. Abaeva D. Yu. Nechipurenko S. I. Obydenniy A. N. Sveshnikova A. M. Shibeko |
| author_sort | M. A. Panteleev |
| collection | DOAJ |
| description | This year marks the 50th anniversary of the first publication about blood plasma microparticles. Initially considered as cell fragments or “platelet dust”, extracellular vesicles currently attracted the attention of biochemists, biophysicists, physicians, pharmacists around the world. They are heterogeneous in structure and derived from many cell types, express different antigen and contain variety of biomolecules that determines wide range of biological activity, including procoagulant, regenerative, immunomodulating, and others. They play an important role in the pathophysiology of different diseases and conditions – from infarction, injuries and pregnancies to the “graft versus host” disease. The vesicles as medicaments and their carriers, as well as the drugs that affect them, are a rapidly developing field of research. |
| first_indexed | 2024-04-09T20:25:22Z |
| format | Article |
| id | doaj.art-52289ad32d2e417385357d4d28a19823 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:25:22Z |
| publishDate | 2017-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-52289ad32d2e417385357d4d28a198232023-03-30T20:15:11ZrusABV-pressОнкогематология1818-83462413-40232017-04-01121627010.17650/1818-8346-2017-12-1-62-70230Physiology and pathology of extracellular vesiculesM. A. Panteleev0A. A. Abaeva1D. Yu. Nechipurenko2S. I. Obydenniy3A. N. Sveshnikova4A. M. Shibeko5National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunnology named after Dmitry Rogachev, Ministry of Health of Russia; Center for Theoretical Problems of Physico-Chemical Pharmacology RAS; Lomonosov Moscow State University; Moscow Institute of Physics and Technology (State University);Center for Theoretical Problems of Physico-Chemical Pharmacology RAS;National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunnology named after Dmitry Rogachev, Ministry of Health of Russia; Center for Theoretical Problems of Physico-Chemical Pharmacology RAS; Lomonosov Moscow State University;National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunnology named after Dmitry Rogachev, Ministry of Health of Russia; Center for Theoretical Problems of Physico-Chemical Pharmacology RAS;National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunnology named after Dmitry Rogachev, Ministry of Health of Russia; Center for Theoretical Problems of Physico-Chemical Pharmacology RAS; Lomonosov Moscow State University;Center for Theoretical Problems of Physico-Chemical Pharmacology RAS;This year marks the 50th anniversary of the first publication about blood plasma microparticles. Initially considered as cell fragments or “platelet dust”, extracellular vesicles currently attracted the attention of biochemists, biophysicists, physicians, pharmacists around the world. They are heterogeneous in structure and derived from many cell types, express different antigen and contain variety of biomolecules that determines wide range of biological activity, including procoagulant, regenerative, immunomodulating, and others. They play an important role in the pathophysiology of different diseases and conditions – from infarction, injuries and pregnancies to the “graft versus host” disease. The vesicles as medicaments and their carriers, as well as the drugs that affect them, are a rapidly developing field of research.https://oncohematology.abvpress.ru/ongm/article/view/232extracellular microvesiclesexosomesectosomesprocoagulant activity |
| spellingShingle | M. A. Panteleev A. A. Abaeva D. Yu. Nechipurenko S. I. Obydenniy A. N. Sveshnikova A. M. Shibeko Physiology and pathology of extracellular vesicules Онкогематология extracellular microvesicles exosomes ectosomes procoagulant activity |
| title | Physiology and pathology of extracellular vesicules |
| title_full | Physiology and pathology of extracellular vesicules |
| title_fullStr | Physiology and pathology of extracellular vesicules |
| title_full_unstemmed | Physiology and pathology of extracellular vesicules |
| title_short | Physiology and pathology of extracellular vesicules |
| title_sort | physiology and pathology of extracellular vesicules |
| topic | extracellular microvesicles exosomes ectosomes procoagulant activity |
| url | https://oncohematology.abvpress.ru/ongm/article/view/232 |
| work_keys_str_mv | AT mapanteleev physiologyandpathologyofextracellularvesicules AT aaabaeva physiologyandpathologyofextracellularvesicules AT dyunechipurenko physiologyandpathologyofextracellularvesicules AT siobydenniy physiologyandpathologyofextracellularvesicules AT ansveshnikova physiologyandpathologyofextracellularvesicules AT amshibeko physiologyandpathologyofextracellularvesicules |